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ACEA

ACEA Struktur
273734-07-9
CAS-Nr.
273734-07-9
Englisch Name:
ACEA
Synonyma:
ACEA;2'-CHLORO-AEA;ARACHIDONYL-2-CHLOROETHYLAMIDE;ARACHIDONYL-2'-CHLOROETHYLAMIDE;ARACHIDONOYL 2'-CHLOROETHYLAMIDE;N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;Propanamide, 3-chloro-N-(4Z,7Z,10Z,13Z)-4,7,10,13-nonadecatetraen-1-yl-
CBNumber:
CB0484073
Summenformel:
C22H36ClNO
Molgewicht:
365.98
MOL-Datei:
273734-07-9.mol

ACEA Eigenschaften

storage temp. 
−20°C
L?slichkeit
DMSO: soluble
Aggregatzustand
oil
Farbe
pale yellow

Sicherheit

WGK Germany  3

ACEA Chemische Eigenschaften,Einsatz,Produktion Methoden

Enzyminhibitor

This synthetic CB1 receptor agonist and anandamide (N- arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69- 4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki = 1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM). ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster ovary cells expressing the human CB1 receptor. It also increases the binding of [35S]GTPgS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. ACEA produces hypothermia in mice, an effect that is inhibited by co-administration of the CB1 receptor antagonist SR141716A.

ACEA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ACEA Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 15)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037
3bsc@sina.com China 15838 69
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80

  • ARACHIDONYL-2'-CHLOROETHYLAMIDE
  • ARACHIDONYL-2-CHLOROETHYLAMIDE
  • ARACHIDONOYL 2'-CHLOROETHYLAMIDE
  • N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE
  • ACEA
  • 2'-CHLORO-AEA
  • Propanamide, 3-chloro-N-(4Z,7Z,10Z,13Z)-4,7,10,13-nonadecatetraen-1-yl-
  • 273734-07-9
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