9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat)
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- CAS-Nr.
- 312-93-6
- Bezeichnung:
- 9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat)
- Englisch Name:
- DEXAMETHASONE SODIUM PHOSPHATE
- Synonyma:
- EGP437;EGP 437;EGP-437;wymesone;neodecadron;betnelanphosphate;oradexonphosphate;Hexadrol phosphate;examethasonephosphate;dexamethasonephosphate
- CBNumber:
- CB0500878
- Summenformel:
- C22H30FO8P
- Molgewicht:
- 472.44
- MOL-Datei:
- 312-93-6.mol
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9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Eigenschaften
- Schmelzpunkt:
- 154-157°C
- Siedepunkt:
- 669.6±65.0 °C(Predicted)
- Dichte
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 1.67±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Light Brown
- Stabilit?t:
- Hygroscopic, Moisture Sensitive
- Major Application
- pharmaceutical (small molecule)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
62 |
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| WGK Germany |
WGK 3 |
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| HS Code |
2937220000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Repr. 2 |
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| Toxizit?t |
dni-rat-ipr 3 mg/kg JOENAK 62,527,74 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H361 |
Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Reproduktionstoxizit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
| H373 |
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 2 |
Warnung |
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P260, P314, P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P281 |
Vorgeschriebene pers?nliche Schutzausrüstung verwenden. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P314 |
Bei Unwohlsein ?rztlichen Rat einholen / ?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. It was found that liposomal DXM-P inhibited both chronic inflammation and joint destruction, whereas free DXM-P failed to prevent joint destruction.
Definition
ChEBI: A steroid phosphate that is the 21-O-phospho derivative of dexamethasone.
Sicherheitsprofil
An experimental teratogen. Otherexperimental reproductive effects. Mutation data reported.When heated to decomposition it emits toxic fumes of F-and POx.
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 104)Lieferanten
312-93-6(9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat))Verwandte Suche:
Desoximetason
Dexamethason-21-(3-phenylpropionat)
Dexamethason-21-pivalat
Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-[(3-sulfobenzoyl)oxy]-, Mononatriumsalz, (11β,16α)-
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17-valerat
9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-dien-3,20-dion
17,21-Dihydroxy-16α-methylpregna-1,4,9(11)-trien-3,20-dion
Dexamethason-21-acetat
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat)
Betamethason
17-α,21-Dihydroxy-16-α-methylpregna-1,4,9(11)-trien-3,20-dion-21-acetat
Phosphorsure, Isooctylester
Doxibetasol
Isoflupredon
Hexadecyldihydrogenphosphat
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat)
Dexamethason
- (11β,16α)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione
- Dexamethasone Phosphate (200 mg)K0E2750.996mg/mg(dr)
- ,21-(dihydrogenphosphate)
- betnelanphosphate
- [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate
- [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] dihydrogen phosphate
- [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] dihydrogen phosphate
- Dexamethasone Phosphate (200 mg)
- dexamethasone21-orthophosphate
- dexamethasonephosphate
- neodecadron
- oradexonphosphate
- wymesone
- 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
- Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11,17-Dihydroxy-16-Methyl-21-(Phosphonooxy)-,(11Beta,16Alpha)-
- Dexamethasone 21-dihydrogen phosphate
- Dexamethasone orthophosphate
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11β,16α)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) (8CI)
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-phosphate (6CI)
- 9-Fluoro-11β,17-dihydroxy-16α-methyl-21-phosphonooxypregna-1,4-diene-3,20-dione
- Dexamethasone 21-Phosphate D4Q: What is
Dexamethasone 21-Phosphate D4 Q: What is the CAS Number of
Dexamethasone 21-Phosphate D4 Q: What is the storage condition of
Dexamethasone 21-Phosphate D4 Q: What are the applications of
Dexamethasone 21-Phosphate D4
- Dexamethasone Phosphate (1177000)
- EGP 437
- EGP437
- EGP-437
- Hexadrol phosphate
- 9-fluoro-11β,17-dihydroxy-16β-methyl-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate (betamethasone phosphate),
- Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11b,16a)
- examethasonephosphate
- 1, 4-PREGNADIEN-9α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE 21-PHOSPHATE
- 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
- Dexamethasone Hydrogen Phosphate
- Dexamethasone phosphate (EP impurity D)
- Dexamethasone phosphate (Standard)
- Dexamethasone phosphate (EP Impurity C)
- 312-93-6
- C22H30FO8P
- Drug Analogues
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- Organics
