2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC₅₀s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (K_is = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC₅₀ value of 7.7 μM independent of MAO-A activity.

Verwenden

Antidepressive;Monoamine oxidase inhibitor

Biologische Aktivit?t

A highly selective reversible inhibitor of monoamine oxidase type A.

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19956	58
Shaanxi Dideu New Materials Co. Ltd	+86-18192503167 18192503167	1036@dideu.com	China	10920	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53803	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65

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• PIRLINDOLE MESYLATE
• 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole
• 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole
• Pirlindol
• Pirlindol [inn-spanish, french]
• Pirlindolum
• Pirlindolum [inn-latin]
• Unii-V39yph45fz
• 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
• 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole methanesulfonate
• 1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl-
• Pirlindole free base
• Pyrazidol
• Ombitasvir Impurity 6
• Pirlindole
• 60762-57-4
• C15H18N2CH3SO3H
• Monoamine Oxidase