2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure
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- CAS-Nr.
- 76-54-0
- Bezeichnung:
- 2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure
- Englisch Name:
- 2',7'-Dichlorofluorescein
- Synonyma:
- DICHLOROFLUORESCEIN;2,7-DICHLOROFLUORESCEIN;FLUORESCEIN 27;2',7'-Dichloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;DCDHF;Fluorescein 548;3,6-DICHLOROFLUORAN;2,7-Dichorofluorescin;DICHLOROFLUORESCEIN TS;FLUORESCEIN DICHLORIDE
- CBNumber:
- CB0690319
- Summenformel:
- C20H10Cl2O5
- Molgewicht:
- 401.2
- MOL-Datei:
- 76-54-0.mol
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2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure Eigenschaften
- Schmelzpunkt:
- 280 °C (dec.)(lit.)
- Siedepunkt:
- 514.77°C (rough estimate)
- Dichte
- 0.79 g/mL at 20 °C
- chüttdichte
- 390kg/m3
- Brechungsindex
- 1.5300 (estimate)
- Flammpunkt:
- 12°C (53.6°F)
- storage temp.
- room temp
- L?slichkeit
- alcohol: passes test
- pka
- 4.46(at 25℃)
- Aggregatzustand
- crystalline
- Farbe
- orange to red-brown, powder
- S?ure-Base-Indikators(pH-Indikatoren)
- 4.0 (colorless) - 6.6 (green)
- Wasserl?slichkeit
- Soluble in ethanol and methanol. Slightly dimethyl sulfoxide. Insoluble in water.
- maximale Wellenl?nge (λmax)
- 509nm
- BRN
- 58009
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- Major Application
- Electroluminescent devices, sol-gel silica films, integrated circuits, photoresists, lithographic
printing plates, recording material, LED devices, photoconductors, Solid-state dye laser, lithographic printing plates, inks, Fluorescent pH sensors, emissive probes, chemotherapeutic treatment of disease, phototherapeutic treatment of disease, photodynamic treatment of disease
- InChI
- 1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H
- InChIKey
- NZVMJBGGAQSNLI-UHFFFAOYSA-N
- SMILES
- Oc1cc2Oc3cc(O)c(Cl)cc3C4(OC(=O)c5ccccc45)c2cc1Cl
- CAS Datenbank
- 76-54-0(CAS DataBase Reference)
- EPA chemische Informationen
2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36:Reizt die Augen.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
red to yellow solid
Verwenden
2',7'-Dichlorofluorescein is used as an indicator and as a cellular antioxidant activity. It is also used for the determination of carbohydrates and hydrogen peroxide by fluorescence densitometry and chemiluminescence respectively. It is used as an indicator for argentometry by Fajans method. It is also involved in the cellular antioxidant activity assay. It is utilized as an additive in fluorescence and laser studies.
Definition
2',7'-dichlorofluorescein is a member of 2-benzofurans. It has a role as a fluorochrome. It derives from a fluorescin.
Application
2',7'-dichlorofluorescein has been used as an oxidation-sensitive fluorescent probe to measure ROS (reactive oxygen species) formation in cells.
Biologische Aktivit?t
2',7'-dichlorofluorescein is an oxidation-sensitive fluorescent probe. 2′7′-dichlorofluorescein diacetate is oxidized to 2′7′-dichlorofluorescein in the presence of ROS (reactive oxygen species).
Einzelnachweise
[1] Chander Hans. “2’,7’-Dichlorofluorescein (DCF) or 2’,7’-dichlorodihydrofluorescein diacetate (DCFH2-DA) to measure reactive oxygen species in erythrocytes.” Biomedicine & Pharmacotherapy (2021): 111512.
2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 331)Lieferanten
76-54-0(2-(2,7-Dichlor-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoesure)Verwandte Suche:
- TIMTEC-BB SBB008847
- 2',7'-DICHLOROFLUORESCEIN
- 2',7'-DICHLORO-FLUORESCEINE
- 2',7'-DICHLORO-3',6'-DIHYDROXYSPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-3-ONE
- 2',7'-DICHLORO-3,6-FLUORANDIOL
- 2',7'-Dichlorofluorofluorescein
- 2',7'-DICHLOROFLUORESCEIN ACS REAGENT
- 2' 7'-DICHLOROFLUORESCEIN A.C.S. REAGE&
- 2',7'-DICHLOROFLUORESCEIN, FLUORESCENCE INDICATOR
- 2,7-DICHLOROFLUORESCEIN SOLUTION, READY- TO-USE
- 2',7'-DICHLOROFLUORESCEIN [FOR FLUORESCENT INDICATOR]
- 2,7-DICHLOROFLUORESCEIN ADSORPTION INDICATOR
- 2',7'-DICHLOROFLUORESCEIN, LASER GRADE
- 2,7-DichloroFluorosceinGr
- 2,7-DICHLORO FLUORESCEIN GR
- 2',7'-Dichlorofluorescein, laser grade, pure
- 2',7'-Dichlorofluorescein, pure
- 2',7'-DICHLOROFLUORESCEIN REAGENT (ACS)
- DICHLOROFLUORESCEIN SOLUTION 0.1% IN ALCOHOL
- 2',7'-Dichlorofluorescein, Reagent
- 2,7-Dichloro-3,6-dihydroxyspiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
- DC orange 25 (2',7'-dichlorofluorescein)
- 2',7'-Dichlorofluorescein,pure,laser grade
- D and C Orange 25
- D and C Orange No. 25
- 2',7'-DICHLOROFLUORE
- [for Fluorescent indicator]
- 2',7'-Dichlorofluorescein
- 2',7'-DICHLOROFLUORESCEIN INDICATOR ACS
- 2’,t-dichlorofluorescein
- 9’-[9H]xanthen]-3-one,2’,7’-dichloro-3’,6’-dihydroxy-Spiro[isobenzofuran-1(3H)
- dcorange25(fluorescein548)
- spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,2’,7’-dichloro-3’,6’-dihydroxy
- 2-(2,7-dichloro-6-hydroxy-3-oxo-3-H-xanthen-9-yl)benzoic acid
- Dichloro (R) fluorescein
2',7'-Dichloro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
- Fluorescein, 2′,7′-dichloro-
- 2′,7′-dichloro Uorescein
- D And C Borange No. 25
- 2',7'-Dichlorofluorescein, CP
- DICHLOROFLUORESCEIN SOLUTION, 1% in REAGENT ALCOHOLDICHLOROFLUORESCEIN SOLUTION, 1% in REAGENT ALCOHOLDICHLOROFLUORESCEIN SOLUTION, 1% in REAGENT ALCOHOL
- 2',7'-DICHLOROFLUORESCEIN, REAGENT (ACS)2',7'-DICHLOROFLUORESCEIN, REAGENT (ACS)2',7'-DICHLOROFLUORESCEIN, REAGENT (ACS)
- 2',7'-DichL
- orofL
- uorescein
- 2',7'-Dichlorofluorescein, 98%, reagent grade
- 2',7'-Dichlorofluorescein [for Fluorescent indicator]>
- 2',7'-Dichlorofluorescein [Fluorescent indicator
- 2,7-Dichlorofluoresceine, ACS reagent
- 2,7-Dichlorofluorescein (DCF) extrapure AR, ACS, 90%
- 2'',7''-dichloro-3'',6''-dihydroxyspiro[2-benzofuran-3,9''-xanthene]-1-one
- 2,7-DICHLORO FLUORESCEIN AR/ACS
- DICHLORO (R) FLUORESCEIN
- DICHLOROFLUORESCEIN TS
- FLUORESCEIN DICHLORIDE
- FLUORESCEIN 27
- 3,6-DICHLOROFLUORAN
- Fluorescein 548
- dcorange25(fluorescein
