IBUTILIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Cardiac depressant
(anti-arrhythmic).
Allgemeine Beschreibung
Ibutilide, N-{4-[4-(ethylheptylamino)-1-hydroxybutyl]phenyl}methanesulfonamide (Corvert), aclass III antiarrhythmic belonging to the methanesulfonanilideclass of agents, is indicated for rapid conversion ofatrial fibrillation or atrial flutter to normal sinus rhythm.Unlike dofetilide, it is not highly specific for the delayedrectifier potassium currents (Ikr) and does have some affinityfor sodium channels.
Clinical Use
Ibutilide (Corvert) is another methanesulfonanilide derivative , but unlike sotalol, it lacks
any β-adrenergic blocking activity. Like sotalol, it exhibits electrophysiologic effects characteristic of
Class III. Ibutilide is used only by intravenous infusion as its fumarate salt.
IBUTILIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
