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Exo-1

Exo-1 Struktur
75541-83-2
CAS-Nr.
75541-83-2
Englisch Name:
Exo-1
Synonyma:
EXO1;EOX 1;NSC 214045;Exo1, 10 mM in DMSO;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-Fluoro-benzoylami;Exo 1 >=98% (HPLC), solid;Exo1 - CAS 75541-83-2 - Calbiochem;Exo1,inhibit,Exo-1,Exo 1,Inhibitor
CBNumber:
CB0713355
Summenformel:
C15H12FNO3
Molgewicht:
273.26
MOL-Datei:
75541-83-2.mol

Exo-1 Eigenschaften

storage temp. 
+2C to +8C
L?slichkeit
DMSO: 19 mg/mL, soluble
Aggregatzustand
solid
Farbe
White to off-white
InChI
1S/C15H12FNO3/c1-20-15(19)12-4-2-3-5-13(12)17-14(18)10-6-8-11(16)9-7-10/h2-9H,1H3,(H,17,18)
InChIKey
KIAPWMKFHIKQOZ-UHFFFAOYSA-N
SMILES
COC(=O)c1ccccc1NC(=O)c2ccc(F)cc2

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

Exo-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 μM). It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.

Biochem/physiol Actions

Exo 1 is a cell-permeable methylanthranilate analog that promotes the release of adenosine diphosphate (ADP)-ribosylation factor (ARF) 1 from Golgi membranes. It also inhibits the membrane trafficking between the endoplasmic reticulum (ER) and the Golgi bodies.

Exo-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Exo-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 63)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30224 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39039 58
Aladdin Scientific

tp@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037
3bsc@sina.com China 15838 69
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80

  • 4-FLUORO-BZ-2-ABZ-OME
  • 2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
  • 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
  • 2-(4-Fluoro-benzoylami
  • 2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate
  • EOX 1
  • EXOCYTIC INHIBITOR 1
  • EXO1
  • Exo1, Exocytic Inhibitor 1, 2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester
  • EXOCYTIC INHIBITOR 1;NSC 214045;EXO 1;EXO-1
  • NSC 214045
  • Exo1 - CAS 75541-83-2 - Calbiochem
  • Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester
  • Exo 1 >=98% (HPLC), solid
  • Exo1,inhibit,Exo-1,Exo 1,Inhibitor
  • Methyl 2-(4-fluorobenzamido)benzoate
  • Exo1, 10 mM in DMSO
  • 75541-83-2
  • C15H12NFO3
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