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N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin

PROTRIPTYLINE Struktur
438-60-8
CAS-Nr.
438-60-8
Bezeichnung:
N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin
Englisch Name:
PROTRIPTYLINE
Synonyma:
Triptil;Vivactil;Amimetilina;Protriptylin;PROTRIPTYLINE;Protryptyline;Protriptyline-d6;Protriptyline 13CD3;DIBENZO(A,D)CYCLOHEPTENE-5-PROPYLAMINE,N-METHYL-;3-(dibenzo(a,d)cyclohepten-5-yl)propylmethylamine
CBNumber:
CB0774981
Summenformel:
C19H21N
Molgewicht:
263.38
MOL-Datei:
438-60-8.mol

N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin Eigenschaften

Siedepunkt:
396.62°C (rough estimate)
Dichte
0.9076 (rough estimate)
Brechungsindex
1.7500 (estimate)
pka
8.2(at 25℃)
EPA chemische Informationen
Protriptyline (438-60-8)

Sicherheit

Giftige Stoffe Daten 438-60-8(Hazardous Substances Data)

N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Protriptyline is a powerful antidepressant, the mechanism of action of which is not known. It is not a MAO inhibitor and does not stimulate the CNS. It begins to act much faster and acts much longer than imipramine or amitriptyline. Protriptyline does not possess sedative tranquilizing properties. It is used in clinical conditions for treating severe depression.

Mechanism of action

Protriptyline exhibits high selectivity for the NE transporter, but with less potency than desipramine. Its mechanism of action is similar to that of desipramine. Minimal effect on 5-HT reuptake has been observed.

Stoffwechsel

Protriptyline is a dibenzocycloheptriene TCA that differs from the other tricyclics by having an unsaturated ethylene bridge joining the two aromatic rings and a secondary aminopropyl side chain. Protriptyline is completely absorbed from the GI tract and slowly eliminated. Metabolism data are limited for protriptyline, but it is most likely to be metabolized via the same pathways as the other TCAs are. Very little drug is excreted in the feces via the bile.

N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 30)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
Shaanxi Didu New Materials Co. Ltd
+86-86-17392712697 +8617792793228
1069@dideu.com China 8585 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19956 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739
info@dycnchem.com China 53803 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833
info@sagechem.com China 10266 58
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57422 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 029-029-029-81148696 18161915376
1040@dideu.com China 9999 58
TargetMol Chemicals Inc. 4008200310 15002144251
marketing@tsbiochem.com China 24955 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900
judy.xia@synzest.com China 12582 58

438-60-8(N-Methyl-5H-dibenzo(a,d)cyclohep-ten-5-propanamin)Verwandte Suche:


  • PROTRIPTYLINEHYDROCHLORIDE,1.0MG/ML(FREEBASE)INMETHANOL
  • DIBENZO(A,D)CYCLOHEPTENE-5-PROPYLAMINE,N-METHYL-
  • N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propan-1-amine
  • Protriptyline-d6
  • PROTRIPTYLINE
  • 3-(5H-Dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine
  • 5-(3-Methylaminopropyl)-5H-Dibenzo[a,d]cycloheptene
  • 5H-Dibenzo[a,d]cycloheptene-5-propanamine, N-methyl-
  • 5H-Dibenzo[a,d]cycloheptene-5-propylamine, N-methyl-
  • 7-(3-Methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene
  • Amimetilina
  • N-3-(5H-Dibenzo(a,d)cyclohepten-5-yl)propyl-N-methylamine
  • N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine
  • Protryptyline
  • Triptil
  • Vivactil
  • 3-(dibenzo(a,d)cyclohepten-5-yl)propylmethylamine
  • 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
  • Protriptylin
  • Protriptyline 13CD3
  • 438-60-8
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