ANTI-PRO-BDNF
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- CAS-Nr.
- Englisch Name:
- ANTI-PRO-BDNF
- Synonyma:
- ANTI-PRO-BDNF;ANTI-PRO-BRAIN-DERIVED NEUROTROPHIC FACTOR;Anti-Pro-BDNF antibody produced in rabbit
- CBNumber:
- CB0822325
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-PRO-BDNF Eigenschaften
- storage temp.
- −20°C
- Aggregatzustand
- lyophilized powder
- Biologische Quelle
- rabbit
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| WGK Germany |
WGK 3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
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ANTI-PRO-BDNF Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Verwenden
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Allgemeine Beschreibung
The brain derived neurotrophic factor (BDNF) gene is mapped to human chromosome 11p14.1. The gene encodes a precursor protein, proBDNF. Mature BDNF (mBDNF) is synthesized by post-translational cleavage of proBDNF. Does not cross react with pro-NGF, pro-NT-3, or mature BDNF.
Biochem/physiol Actions
Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins. Neurotrophins are synthesized as preproneurotrophin precursors and further processed to proneurotrophins and subsequently to neurotrophins. BDNF is expressed in the developing and the mature brain. The influence of BDNF is mediated by its binding to TrkB receptor and sometimes the receptor p75NTR. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.
ANTI-PRO-BDNF Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-PRO-BDNF Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 7)Lieferanten
- Anti-Pro-BDNF antibody produced in rabbit
- ANTI-PRO-BDNF
- ANTI-PRO-BRAIN-DERIVED NEUROTROPHIC FACTOR
