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Deserpidin

Deserpidine Struktur
131-01-1
CAS-Nr.
131-01-1
Bezeichnung:
Deserpidin
Englisch Name:
Deserpidine
Synonyma:
Harmonyl;Raunormine;Canescine;Reserpidine;Recanescine;DESERPIDINE;Di She Ping;Reserpine Impurity 3;Deserpidine USP/EP/BP;Deserpidine, 10 mM in DMSO
CBNumber:
CB0834483
Summenformel:
C32H38N2O8
Molgewicht:
578.65
MOL-Datei:
131-01-1.mol

Deserpidin Eigenschaften

Schmelzpunkt:
228-232°; mp 230-232°; mp 138° and 226-232° with resolidification at 175°
alpha 
D20 -163° (c = 0.5 in pyridine)
Siedepunkt:
638.28°C (rough estimate)
Dichte
1.2277 (rough estimate)
Brechungsindex
1.6260 (estimate)
storage temp. 
-20°C Freezer
L?slichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
6.68 in 40% methanol
Farbe
White to Off-White
InChIKey
CVBMAZKKCSYWQR-TVZLAKDQNA-N
SMILES
[C@]12([H])C[C@@]3([H])[C@]([H])(C[C@@H](OC(=O)C4C=C(C(OC)=C(OC)C=4)OC)[C@H](OC)[C@H]3C(=O)OC)CN1CCC1C3=C(C=CC=C3)NC2=1 |&1:0,3,5,8,24,27,r|
CAS Datenbank
131-01-1(CAS DataBase Reference)
NIST chemische Informationen
Deserpidine(131-01-1)

Sicherheit

Deserpidin Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Crystalline solid; exists in three crystallineforms; mp 228–232°C (442.4–449.6°F); soluble in chloroform and methanol, insolublein water; pK 6.68 in saturated solution of40% methanol in water.

Verwenden

Deserpidine is found and extracted fromthe roots of Rauwolfia canescens L., andApocyanaceae. Therapeutically, it is used asan antihypertensive agent.

Health Hazard

The pharmacological properties of deserpi dine are similar to those of reserpine, causingsedation and tranquilization. Toxic effectsfrom high doses include drowsiness, depres sion, nausea, diarrhea, abdominal cramps,and hypotension. It is less toxic than reserpine. However, the poisoning effects may begreater than those of other Rauwolfia alka loids, such as rescinnamine. An oral LD50value in mice is 500 mg/kg.There is some evidence of its carcinogenic actions in animals and humans. Ratsgiven oral doses of 54 mg/kg over 77 weeksdeveloped blood tumor. In humans, it mayproduce tumors in skin and appendages.Cancer-causing properties of deserpidine,however, are not yet fully established.

Deserpidin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Deserpidin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 113)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17346 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10236 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30225 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665
dominicguo@gk-bio.com CHINA 9414 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739
info@dycnchem.com China 52705 58

131-01-1(Deserpidin)Verwandte Suche:


  • methyl 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
  • DESERPIDINE
  • Canescine
  • Recanescine
  • Reserpidine
  • (1S,2R,3R,4aS,13bR,14aS)-2-methoxy-3-(3,4,5-trimethoxybenzoyl)oxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester
  • (1S,2R,3R,4aS,13bR,14aS)-Methyl 2-Methoxy-3-((3,4,5-triMethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
  • Reserpine Impurity 3
  • Deserpidine Solution, 100ppm
  • Yohimban-16-carboxylic acid, 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
  • Deserpidine USP/EP/BP
  • Methyl (1S,2R,3R,4aS,13bR,14aS)-2-methoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
  • Deserpidine, 10 mM in DMSO
  • methyl (3beta,16beta,17alpha,18beta,20alpha)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
  • Methyl (1S,2R,3R,4aS,13bR,14aS)-2-methoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
  • Di She Ping
  • Shegen Pingding: Dishaping
  • Harmonyl
  • Raunormine
  • 131-01-1
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