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Benoxaprofen

Uniprofen Struktur
51234-28-7
CAS-Nr.
51234-28-7
Bezeichnung:
Benoxaprofen
Englisch Name:
Uniprofen
Synonyma:
Opren;Oraflex;Coxigon;Inflamid;LY-90459;Uniprofen;LRCL-3794;NSC 299582;Aids128826;Lilly-90459
CBNumber:
CB0875361
Summenformel:
C16H12ClNO3
Molgewicht:
301.73
MOL-Datei:
51234-28-7.mol

Benoxaprofen Eigenschaften

Schmelzpunkt:
189.5°C
Siedepunkt:
446.2±30.0 °C(Predicted)
Dichte
1.2411 (rough estimate)
Brechungsindex
1.6470 (estimate)
storage temp. 
Refrigerator
L?slichkeit
DMSO: slightly; Methanol: slightly, sonicated
Aggregatzustand
A solid
pka
4.36±0.30(Predicted)
Farbe
Cream solid from EtOH

Sicherheit

Toxizit?t LD50 oral in rat: 118mg/kg

Benoxaprofen Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A non-steroidal anti-inflammatory ophthalmic agent.

Definition

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group. It was used as a non-steroidal anti-inflammatory drug until 1982 when it was withdrawn from the market due to adverse side-effects inc uding liver necrosis, photosensitivity, and carcinogenicity in animals.

Weltgesundheitsorganisation (WHO)

Benoxaprofen, a nonsteroidal antiinflammatory agent, was introduced in 1980 for the treatment of rheumatic disorders. Following reports of serious adverse effects, some of which were fatal, it was withdrawn in several countries prior to worldwide withdrawal by the manufacturer in 1982.

Sicherheitsprofil

Poison by ingestion, subcutaneous, and intraperitoneal routes. Moderately toxic to humans by ingestion.Human systemic effects by ingestion: jaundice and gynecomastia (excessive development of the male mammary glands), changes in kidney tubules, decreased

Benoxaprofen Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Benoxaprofen Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 50)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750
info@finetechnology-ind.com China 9539 58
Hunan Jibang Biological Technology Co., LTD
+8613776644403
sales02@kingboomtech.com China 1804 58
Shaanxi Didu New Materials Co. Ltd
+86-86-17392712697 +8617792793228
1069@dideu.com China 8609 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896
cbc@coresyn.com China 9984 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850
market18@leapchem.com China 43333 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203
info@chemextension.com China 42056 58
NANJING YINGWEN BIOTECHNOLOGY CO LTD
+8613382787392
sales@aeechem.com China 10001 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58

51234-28-7(Benoxaprofen)Verwandte Suche:


  • Coxigon
  • Oraflex
  • Uniprofen
  • 2-(2-(4-chlorophenyl)benzo[d]oxazol-5-yl)propanoic acid
  • 2-[2-(4-Chlorophenyl)benzoxazol-5-yl]-propanoic Acid
  • dl-Benoxaprofen
  • NSC 299582
  • 2-(4-Chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
  • Compound-90459
  • Lilly-90459
  • LRCL-3794
  • 2-(2-(4-Chlorophenyl)-1,3-benzoxazol-5-yl)propanoic acid
  • 2-(p-Chlorophenyl)-.alpha.-methyl-5-benzoxazoleacetic acid
  • 5-Benzoxazoleacetic acid, 2-(4-chlorophenyl)-.alpha.-methyl-
  • Aids128826
  • Aids-128826
  • Inflamid
  • 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid
  • 5-Benzoxazoleacetic acid, 2-(4-chlorophenyl)-α-methyl-
  • Benoxaphen. Compound 90459
  • LY-90459
  • 4H-1-Benzopyran-4-one,7-hydroxy-3-(trifluoromethyl)-
  • inflammation,LRCL-3794,monocyte migration,inhibit,COX,Cyclooxygenase,LRCL 3794,LRCL3794,Inhibitor,lipoxygenase,Benoxaprofen,antipyretic compound
  • 2-[2-(4-Chlorophenyl)-5-benzoxazolyl]propanoic Acid
  • Benoxaprofen, 10 mM in DMSO
  • Opren
  • 51234-28-7
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Isotope Labelled Compounds
  • Phamaceuticals
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