2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on
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- CAS-Nr.
- 17952-82-8
- Bezeichnung:
- 2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on
- Englisch Name:
- 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one
- Synonyma:
- 1,2,3,4-Tetrahydronorharman-1-one;3,4-Dihydro-β-carboline-1(2H)-one;1,2,3,4-Tetrahydro-β-carboline-1-one;2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one;2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one;1,2,3,4-Tetrahydronorharman-1-one, 10 mM in DMSO;1H-Pyrido[3,4-b]indol-1-one, 2,3,4,9-tetrahydro-
- CBNumber:
- CB0915201
- Summenformel:
- C11H10N2O
- Molgewicht:
- 186.21
- MOL-Datei:
- 17952-82-8.mol
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2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on Eigenschaften
- Schmelzpunkt:
- 183-185 °C
- Siedepunkt:
- 529.2±39.0 °C(Predicted)
- Dichte
- 1.318±0.06 g/cm3(Predicted)
- L?slichkeit
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- Aggregatzustand
- Cryst.
- pka
- 15.48±0.20(Predicted)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on Chemische Eigenschaften,Einsatz,Produktion Methoden
synthetische
Tryptamine 380 (9.0 g, 56.2 mmol) and triethylamine (13.8 g, 136.3 mmol) were dissolved in warm toluene (800 mL). Under vigorous stirring, a solution of triphosgene (6.7 g, 22.6 mmol) in toluene (35 mL) was added dropwise and the mixture was stirred for a further 20 min at room temperature. Then, HBr (30% in acetic acid; 13 mL) was added and the mixture was refluxed for 30 min. After cooling to room temperature, water (300 mL) and ethyl acetate (300 mL) were added and, after separation of the layers, the aqueous phase was extracted once more with ethyl acetate (300 mL). The combined organic layers were dried over magnesium sulfate and concentrated in vacuo. The residue was recrystallized from methanol/ethyl acetate (1:1) to afford 7.74 g (74%) of 2,3,4,9-tetrahydro-1H-pyrido[ 3,4-b]indol-1-one 382 as a white solid; mp 184°C.
2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 44)Lieferanten
17952-82-8(2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on)Verwandte Suche:
6-Chlor-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-on
2,3,4,9-Tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-on
2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-on
- 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one
- 1,2,3,4-Tetrahydro-β-carboline-1-one
- 3,4-Dihydro-β-carboline-1(2H)-one
- 1,2,3,4-Tetrahydronorharman-1-one
- 1H-Pyrido[3,4-b]indol-1-one, 2,3,4,9-tetrahydro-
- 2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one
- 1,2,3,4-Tetrahydronorharman-1-one, 10 mM in DMSO
- 17952-82-8
