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GLY-ARG-GLY-ASP-SER-PRO-LYS

GLY-ARG-GLY-ASP-SER-PRO-LYS Struktur
111119-28-9
CAS-Nr.
111119-28-9
Englisch Name:
GLY-ARG-GLY-ASP-SER-PRO-LYS
Synonyma:
GRGDSPK;EMD 56574;GRGDSPK - 1 mg;GRGDSPK (EMD 56574);RGD Peptide GRGDSPK;GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
CBNumber:
CB1123649
Summenformel:
C28H49N11O11
Molgewicht:
715.76
MOL-Datei:
111119-28-9.mol

GLY-ARG-GLY-ASP-SER-PRO-LYS Eigenschaften

Dichte
1.59±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
3.60±0.21(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
Biologische Quelle
human
Sequenz
Gly-Arg-Gly-Asp-Ser-Pro-Lys
InChIKey
ZRVZOBGMZWVJOS-VMXHOPILSA-N
SMILES
NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)CN)C(O)=O

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

GLY-ARG-GLY-ASP-SER-PRO-LYS Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-
  • as a blocking peptide to inhibit integrin-fibronectin binding
  • in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
  • for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
  • for the preparation of RGD.Flt23k.NR nanoparticles
  • to determine the involvement of RGD-integrin bonding in cell adhesion process

Allgemeine Beschreibung

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


GLY-ARG-GLY-ASP-SER-PRO-LYS Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 84)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30224 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471;
sales@sarms4muscle.com China 10473 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634
Cecilia@youngshechem.com China 2345 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39040 58
Nanjing TGpeptide
+86-13347807150
support@tgpeptide.com China 3279 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599
info@molchanges.com China 5218 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739
info@dycnchem.com China 53803 58

  • H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH
  • GRGDSPK
  • GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE
  • GLY-ARG-GLY-ASP-SER-PRO-LYS
  • GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE
  • glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine
  • EMD 56574
  • L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-
  • Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
  • Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
  • GRGDSPK (EMD 56574)
  • GRGDSPK - 1 mg
  • RGD Peptide GRGDSPK
  • 111119-28-9
  • C28H49N11O11
  • Extracellular Matrix
  • Extracellular Matrix Peptides and Proteins
  • Cytoskeleton and Extracellular Matrix
  • Cell Signaling and Neuroscience
  • BioChemical
  • Cell Biology
  • peptide
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