2,4-DIHYDROXY-6-METHYLBENZOIC ACID
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- CAS-Nr.
- 480-64-8
- Englisch Name:
- 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
- Synonyma:
- ORSELLINIC ACID;133346;Orsellic acid;o-orsellinicaci;o-orsellinic acid;ORSELLINIC ACID MONOHYDRATE;6-Methyl-2,4-dihydroxybenzoic acid;2-Methyl-4,6-dihydroxybenzoic acid;2,4-DIHYDROXY-6-METHYLBENZOIC ACID;Benzoic acid, 2,4-dihydroxy-6-Methyl-
- CBNumber:
- CB1185500
- Summenformel:
- C8H8O4
- Molgewicht:
- 168.15
- MOL-Datei:
- 480-64-8.mol
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2,4-DIHYDROXY-6-METHYLBENZOIC ACID Eigenschaften
- Schmelzpunkt:
- 173-174°C
- Siedepunkt:
- 257.07°C (rough estimate)
- Dichte
- 1.3037 (rough estimate)
- Brechungsindex
- 1.5090 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Ethyl Acetate (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- pK (25°) 3.90
- Farbe
- White to Pale Gray
- Wasserl?slichkeit
- Soluble in water, dimethyl sulfoxide or 100% ethanol.
- Stabilit?t:
- Hygroscopic
- CAS Datenbank
- 480-64-8
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an IC
50 value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (
Pafr-/-) mouse cerebellar granule cells.
Verwenden
Orsellinic acid is a benzoic acid compound shown to block PAF-mediated neuronal apoptosis.
Definition
ChEBI: A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group.
Biosynthese
One of the simplest polyketide derivatives, orsellinic acid is widely distributed in fungi. It is biosynthesised from an acetate starter unit and three malonyl units, as shown in Figure. Intramolecular condensation of the polyketide chain gives orsellinic acid without further modification.
The biosynthesis of orsellinic acid.
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 137)Lieferanten
480-64-8()Verwandte Suche:
Methyl-2,4-dihydroxy-m-toluat
4-[(4-Methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylsure
[(7-Carboxy-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-9-yl)methyl]hydrogenfumarat
Mycophenolins?ure
3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacy-clotetradecin-1,7(8H)-dion,(S-(E))-
3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat
Methyl-3-chlor-4-hydroxy-6-methylsalicylat
- 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
- ORSELLINIC ACID MONOHYDRATE
- 2,4-Dihydroxy-6-methylbenzoic acid hydrate, 97%
- 2-Methyl-4,6-dihydroxybenzoic acid
- 6-Methyl-2,4-dihydroxybenzoic acid
- Orsellic acid
- o-orsellinic acid
- Benzoic acid, 2,4-dihydroxy-6-Methyl-
- 133346
- o-orsellinicaci
- ORSELLINIC ACID
- 480-64-8
- Inhibitors
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
