POLY(N-ISOPROPYL ACRYLAMIDE) Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
mp 96°C phase transitions at 32°C to insoluble phase
Verwenden
Poly(N-iso-propyl acrylaMide) can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.
Definition
ChEBI: An acrylic macromolecule, arising from poymerisation of N-isopropylamide.
Allgemeine Beschreibung
Poly(
N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer used in biomedical research applications. PNIPAM undergoes a reversible, lower critical solution temperature (LCST) phase transition when heated above 32 °C, transitioning from a soluble to an insoluble material. PNIPAM is also frequently crosslinked to yield hydrogels with reversible, thermal shrinking and swelling. Poly(
N-isopropylacrylamide) is also readily functionalized and has been used as the hydrophilic block in the synthesis of thermoresponsive, amphiphilic block copolymers. Due to the similarity in temperature between the LCST of PNIPAM and the temperature of the human body, PNIPAM materials have been frequently utilized in tissue engineering and controlled drug delivery research applications.
POLY(N-ISOPROPYL ACRYLAMIDE) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
