Bezafibrat
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- CAS-Nr.
- 41859-67-0
- Bezeichnung:
- Bezafibrat
- Englisch Name:
- Bezafibrate
- Synonyma:
- CEDUR;bf-759;bm15075;Befizal;Bezatol;BEZALIP;Benzabet;Difaterol;Bezabrate;Benzabate
- CBNumber:
- CB1188501
- Summenformel:
- C19H20ClNO4
- Molgewicht:
- 361.82
- MOL-Datei:
- 41859-67-0.mol
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Bezafibrat Eigenschaften
- Schmelzpunkt:
- 184 °C
- Siedepunkt:
- 572.1±45.0 °C(Predicted)
- Dichte
- 1.260±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMF: soluble
- Aggregatzustand
- solid
- pka
- 3.29±0.10(Predicted)
- Farbe
- White to Off-White
- Merck
- 14,1195
- Stabilit?t:
- Hygroscopic
- InChI
- InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
- InChIKey
- IIBYAHWJQTYFKB-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C(OC1=CC=C(CCNC(=O)C2=CC=C(Cl)C=C2)C=C1)(C)C
- LogP
- 2.504 (est)
- CAS Datenbank
- 41859-67-0(CAS DataBase Reference)
- EPA chemische Informationen
- Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl- (41859-67-0)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| S-S?tze: |
36 |
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| WGK Germany |
1 |
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| RTECS-Nr. |
UE8755000 |
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| HS Code |
29242990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Toxizit?t |
LD50 oral in rat: 1082mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Bezafibrat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC
50s = 50, 60, and 20 μM for human PPARα, PPARγ, and PPARδ, respectively). It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 μM. Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.
Chemische Eigenschaften
Off-White Solid
Verwenden
Bezafibrate has been used:
- a supplement in the standard diet (SD)for mice to study its effect on diabetes
- to evaluate its effect on hepatitis C virus (HCV) assembly and secretion
- to evaluate its effect on gonadal steroidogenesis andspermatogenesisof zebrafish and also used as standard for HPLC
Bezafibrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Bezafibrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 448)Lieferanten
41859-67-0(Bezafibrat)Verwandte Suche:
- Bezafibrate D6 (dimethyl D6)
- Bezabrate D6 (DiMethyl D6)
- 2-(4-{2-[(4-chlorophenyl)forMaMido]ethyl}phenoxy)-2-Methylpropanoic acid
- Bezafibrate-d6
- BEZAFIBRATE EPB(CRM STANDARD)
- BEZAFIBRATE MM(CRM STANDARD)
- bezafibrat
- bezafibrato
- bf-759
- bm15075
- ([(Chloro-4-benzamido)-2-ethyl]-4-phenoxy)-2-methylpropionic acid
- 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxyl]-2-methylpropanoic Acid
- Befizal
- Bezatol
- Difaterol
- 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid
- 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid
- Bezafibrate,2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid
- 2-[4-[2-(4-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPANOIC ACID
- 2-[4-(2-[4-CHLOROBENZAMIDO]ETHYL)-PHENOXYL]-2-METHYLPROPANOIC ACID
- 2-[4-(2-[4-CHLOROBENZOMIDO]ETHYL)-PHENOXY]-2-METHYLPROPANOIC ACID
- 2-(4-(2-((4-CHLOROBENZOYL)AMINO)ETHYL)PHENOXY)-2-METHYLPROPIONIC ACID
- Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-
- Bezafibrate, 98.0%(LC&T
- Bezafibrate Imp.(EP)
- AURORA KA-851
- BEZAFIBRATE
- BEZALIP
- CEDUR
- 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-propionicaci
- 2-(p-(2-(p-chlorobenzamido)ethyl)phenoxy)-2-methylpropionicacid
- Bezafibrate 41859-67-0
- BezafibrateQ: What is
Bezafibrate Q: What is the CAS Number of
Bezafibrate Q: What is the storage condition of
Bezafibrate Q: What are the applications of
Bezafibrate
- Bezafibrate CRS
- Bezafibrate >
- Bezabrate
- 2-[4-[2-[[(4-chlorophenyl)-oxomethyl]amino]ethyl]phenoxy]-2-methylpropanoate
- Bezafibrate Solution, 100ppm
- 2-(89-Chlorobenzoyl)benzoic&acid
- N-(4-Chlorobenzoyl)-Tyramine (Bezafibrate Intermediate)
- Benzabet
- Bezafibrate in methanol
- Bezafibrate 100 μg/ml Acetonitrile
- Benzabate
- Benzafibrate Impurity
- Bezafibrate, Pan-PPAR agonist
- Bezafibrate, 10 mM in DMSO
- Bezafibrate - Bio-X ?
- Bezafibrate 100 μg/mL in Acetonitrile
- Bezafibrate (Standard)
- 41859-67-0
- 637927-29-7
- 1859-67-0
- C19H20ClNO4
- Cell Biology
- Cell Signaling and Neuroscience
- BioChemical
- Gene Regulation and Expression
