Glutathione Ethyl Ester

92614-59-0

CAS-Nr.: 92614-59-0

Englisch Name:: Glutathione Ethyl Ester

Synonyma:: GSH monoethylester;H-γGlu-Cys-Gly-OEt;L-αGlu-L-Cys-Gly-OEt;H-GLU(CYS-GLY-OET)-OH;Glutathione Ethyl Ester;L-αGlu-L-Cys-Gly-Ethyl OH;γ-Glu-Cys-Gly-OEt, GSH-MEE;GLUTATHIONE MON ETHYL ESTER;Glutatione Reduced Ethyl Ester;GLUTATHIONE REDUCED FORM, ETHYL ESTE

CBNumber:: CB12130580

Summenformel:: C12H21N3O6S

Molgewicht:: 335.38

MOL-Datei:: 92614-59-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 80

Glutathione Ethyl Ester Eigenschaften

Siedepunkt:: 644.3±55.0 °C(Predicted)

Dichte: 1.314±0.06 g/cm3(Predicted)

storage temp.: -20°C

L?slichkeit: PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml

Aggregatzustand: A crystalline solid

pka: 2.21±0.10(Predicted)

Farbe: White to off-white

InChI: 1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1

InChIKey: JKRODHBGNBKZLE-YUMQZZPRSA-N

SMILES: CCOC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(O)=O

Sicherheit

WGK Germany	3
Speicherklasse	11 - Combustible Solids

Glutathione Ethyl Ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Biochem/physiol Actions

Glutathione reduced ethyl ester (GSH-MEE) is a membrane/lipid permeable derivative of GSH that may be used to partially supplement the GSH supply within cells subjected to cysteine and/or GSH depletion. GSH-MEE is hydrolysed by intracellular esterases to release GSH, thereby increases the concentrations of intracellular GSH. It prevents the toxic effects of acetaminophen in animal cells. It protects human lymphoid cells and skin fibroblasts against the damage caused due to radiation.

Glutathione Ethyl Ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Glutathione Ethyl Ester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 80)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
AFINE CHEMICALS LIMITED	+86-571-85134551	info@afinechem.com	China	15081	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33324	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53803	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	+8615051830413	sales.njleonbiotech@gmail.com	China	5482	58

L-αGlu-L-Cys-Gly-OEt
Glycine, L-gamma-glutamyl-L-cysteinyl-, 3-ethyl ester
GLUTATHIONE REDUCED FORM, ETHYL ESTE
L-gamma-Glutamyl-L-cysteinylglycine 3-ethyl ester
H-GLU(CYS-GLY-OET)-OH
Glutathione Ethyl Ester
γ-Glu-Cys-Gly-OEt, GSH-MEE
GSH monoethylester
L-αGlu-L-Cys-Gly-Ethyl OH
Glycine, L-γ-glutamyl-L-cysteinyl-, 3-ethyl ester
Glutathione-monoethyl ester (reduced) H-Glu(Cys-Gly-OEt)-OH
GLUTATHIONE MON ETHYL ESTER
Glutatione Reduced Ethyl Ester
H-γGlu-Cys-Gly-OEt
92614-59-0

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