β-D-Glucosepentaacetat
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- CAS-Nr.
- 604-69-3
- Bezeichnung:
- β-D-Glucosepentaacetat
- Englisch Name:
- β-D-Glucose pentaacetate
- Synonyma:
- BETA-D-GLUCOSE PENTAACETATE;Penta-O-acetyl-β-D-glucopyranose;Beta-Pentacetylglucose;B-D-GLUCOSE PENTAACETATE;beta-D-Glucose Pentaacetate,99%d.e.;Dapagliflozin Impurity 44;Pentaacetyl-β-D-glucopyranose;1,2,3,4,6-PENTA-O-ACETYL-BETA-D-GLUCOSE;1,2,3,4,6-PENTA-O-ACETYL-B-D-GLUCOPYRANOSE;Acetyl 2,3,4,6-tetra-o-acetyl-beta-D-glucopyranoside
- CBNumber:
- CB1217012
- Summenformel:
- C16H22O11
- Molgewicht:
- 390.34
- MOL-Datei:
- 604-69-3.mol
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β-D-Glucosepentaacetat Eigenschaften
- Schmelzpunkt:
- 130-132 °C
- Siedepunkt:
- 435.58°C (rough estimate)
- alpha
- 5 º (c=1, CHCl3)
- Dichte
- 1,274 g/cm3
- Brechungsindex
- 4.5 ° (C=5, CHCl3)
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- chloroform: 0.1 g/mL, clear, colorless
- Aggregatzustand
- Crystalline Powder
- Farbe
- White to off-white
- Geruch (Odor)
- at 100.00%. odorless
- Optische Rotation
- [α]20/D +4.2°, c = 1 in chloroform
- Wasserl?slichkeit
- Soluble in chloroform and methanol. Insoluble in water.
- BRN
- 98851
- InChI
- 1S/C16H22O11/c1-7(17)22-6-12-13(23-8(2)18)14(24-9(3)19)15(25-10(4)20)16(27-12)26-11(5)21/h12-16H,6H2,1-5H3/t12-,13-,14+,15-,16-/m1/s1
- InChIKey
- LPTITAGPBXDDGR-XJGFBQBWSA-N
- SMILES
- CC(O)O[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
- LogP
- 0.634 (est)
- CAS Datenbank
- 604-69-3(CAS DataBase Reference)
- NIST chemische Informationen
- Acetyl 2,3,4,6-tetra-o-acetyl-«beta»-D-glucopyranoside(604-69-3)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H314 |
Verursacht schwere Ver?tzungen der Haut und schwere Augensch?den. |
?tzwirkung auf die Haut |
Kategorie 1B |
Achtung |
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P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P310 |
Sofort GIFTINFORMATIONSZENTRUM/Arzt/ anrufen. |
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β-D-Glucosepentaacetat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R21:Gesundheitssch?dlich bei Berührung mit der Haut.
R36/38:Reizt die Augen und die Haut.
R46:Kann vererbbare Sch?den verursachen.
R62:Kann m?glicherweise die Fortpflanzungsf?higkeit beeintr?chtigen.
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S25:Berührung mit den Augen vermeiden.
Chemische Eigenschaften
white to beige powder
Verwenden
β-D-Glucose Pentaacetate is used in biochemical reaction and also used as an active pharmaceutical intermediate. Further, it is used to stimulate insulin release in rat pancreatic islets.
l?uterung methode
Crystallise the pentaacetate from MeOH or EtOH. It is best purified by recrystallising 160g from 1L of hot 95% EtOH (charcoal) and filtering hot. It is important that as soon as the temperature of the filtrate cools to ~20o it is filtered off. Note that some -D-isomer will crystallise out if a prolonged crystallisation period is allowed. Further crystallisation in this manner and drying in a vacuum over CaCl2 will give pure -D-anomer which has m 132o, [] D 20 + 4o (c 5, CHCl3). [Wolfrom & Thompson Methods in Carbohydrate Chemistry II 212 1963, Academic Press, Krahl & Cori Biochemical Preparations 1 33 1955, Beilstein 17/7 V 319.]
β-D-Glucosepentaacetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
β-D-Glucosepentaacetat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 476)Lieferanten
604-69-3(β-D-Glucosepentaacetat)Verwandte Suche:
- β-1,2,3,4
- PENTAACETYL-BETA-D-GLUCOSE
- PENTA-O-ACETYL-BETA-D-GLUCOPYRANOSIDE
- PENTA-O-ACETYL-BETA-D-GLUCOPYRANOSE
- 1,2,3,4,6-Penta-O-acetylhexopyranose
- beta-D-Glucopyranosyl pentaacetate
- Glucopyranose, pentaacetate, beta-D-
- Pentaacetyl-beta-D-glucopyranose
- b-D-GLUCOSE PENTACETATE
- Penta-O-acetyl-beta-D-glucopyranose
Pentaacetyl-beta-D-glucose
1,2,5,6-Di-O-isopropylidene-D- Mannitol
1,2:5,6-Bis-o-(1-Methylethylidene)-D-Mannitol
1,2-Bis(2,2-Dimethyl-1,3-Dioxolan-4-yl)-1,2-Ethanediol
1,2,3,4,6-Penta-O
- -D-Glucose pentaacetate for synthesis
- 1,2,3,4,6-PENTA-O-ACETYL-BETA-D-GLUCOPYRANOSE
- [(2S,3R,5R,6R)-2,3,5-Triacetyloxy-6-(acetyloxymethyl)oxan-4-yl] acetate
- -D-GlucosePentacetate
- β-D-Glucopyranose pentaacetate
- 1,2,3,4,6-BETA-
- beta-D-Glucose pentaacetate,99+%
- beta-D-g
- lucose Pentaacetate
- 1,2,3,4,6-Penta-O-acet
- β-D-Glucose pentaacetate ,98%
- beta-D-Glucose penta
- β-D-Glucopyranose 1,2,3,4,6-Pentaacetate
- beta-D-Glucose Pentaacetate
Pentaacetyl-beta-D-glucose
- B-D-GLUCOSE PENTAACETATE FOR SYNTHESIS
- 1,2,3,4,6-PENTAACETYL-ALPHA-D-GLUCOSE
- Pentaacetyl-b-D-glucose
- BETA-D-GLUCOSE PENTAACETATE, FOR MICROBI OLOGY
- PENTAACETYL-BETA-D-GLUCOSE 99+%
- ACETIC ACID 2,3,4-TRIACETOXY-6-ACETOXYMETHYL-CYCLOHEXYL ESTER
- beta-D-Glucosepentacetate
- 1,2,3,4,6-pentaacetyl-á-d-glucose
- á-d-glucose pentaacetate
- BETA-D-GLUCOSEAPENTAACETATE
- SS-D-GLUCOSE PENTAACETATE
- 6-Pentacetyl-D-glucose
- BETA-D-GLUCOPYRANOSE-PENTAACETATE
- BETA-D(+)-GLUCOSE PENTAACETATE
- BETA-DEXTROSE PENTAACETATE
- B-D-1,2,3,4,6-PENTA-O-ACETYL-B-GLUCOPYRANOSE
- D-B-GLUCOSE PENTAACETATE
- GLUCOSE PENTAACETATE, B-D-
- b-D-Glucopyranose, 1,2,3,4,6-pentaacetate
- 1,2,3,4,6-PENTA-O-ACETYL-SS-D-GLUCOPYRANOSE
- Beta-D-Glucose Pentaacetate / Beta-Pentacetylglucose
- β-D-Glucose pentaacetate
- eta-D-Glucose Pentaacetate
- β-D-Glucose pentaacetate USP/EP/BP
- β-Pentacetylglucose
- β-Glucose pentaacetate
- 1,2,3,4,6-β-D-Glucose pentaacetate
- beta-dextro-pentaacetyl glucose
- Beta- D-Glucose Pentaacetate CAS 604-69-3
- -D-Glucopyranuronosylamine
- β-D-Glucose Pentaacetate extrapure, 99%
- β-D-(+)-Glucose pentaacetate Beta-D-Glucose pentaacetate
- beta-d-glucopentaacetate
- 1,2,3,4,6-PENTA-O-ACETYL-B-D-GLUCOPYRANOSE
