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MU-CALPAIN

MU-CALPAIN Struktur
CAS-Nr.
Englisch Name:
MU-CALPAIN
Synonyma:
CALPAIN-1;MU-CALPAIN;EC 3.4.22.17;CALPAIN 1 HUMAN;CALPAIN I, HUMAN ERYTHROCYTES
CBNumber:
CB1220687
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

MU-CALPAIN Eigenschaften

storage temp. 
-70°C
Aggregatzustand
aqueous glycerol solution
Specific Activity
≥1000U/mg

Sicherheit

WGK Germany  3
Speicherklasse 10 - Combustible liquids

MU-CALPAIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Human calpain 1 has been used in a study to assess how the crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition. Human calpain 1 has also been used in a study to investigate the synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors.

Biochem/physiol Actions

Caplain 1 is a neutral calcium-dependent cysteine protease containing the EF-hand motif. The protease consists of two subunits; the larger subunit has four domains that are homologous with papain and calmodulin. The smaller subunit has one domain that shares homology with calmodulin. It is activated by micromolar levels of calcium and hence, it is also called as micro-calpain. Its activation leads to cellular protein degradation, neuronal cell degeneration, and autoimmune demyelinating diseases such as multiple sclerosis.

MU-CALPAIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MU-CALPAIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 5)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969
sales@tomums.cn China 4696 58
Merck KGaA --
ordercn@merckgroup.com China 6394 58

  • CALPAIN I, HUMAN ERYTHROCYTES
  • CALPAIN 1 HUMAN
  • CALPAIN-1
  • EC 3.4.22.17
  • MU-CALPAIN
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