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MONOCLONAL ANTI-HNRNP-A1

MONOCLONAL ANTI-HNRNP-A1 Struktur
CAS-Nr.
Englisch Name:
MONOCLONAL ANTI-HNRNP-A1
Synonyma:
FLI-2;HDP-1;HNRPA1;Anti-HNRPA1;Anti-hnRNP-A1;Anti-HNRPA1L3;Anti-MGC102835;MONOCLONAL ANTI-HNRNP-A1;Helix-destabilizing protein;Anti-HNRNPA1 antibody produced in rabbit
CBNumber:
CB1231728
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

MONOCLONAL ANTI-HNRNP-A1 Eigenschaften

storage temp. 
−20°C
Aggregatzustand
buffered aqueous solution
Biologische Quelle
rabbit

Sicherheit

WGK Germany  3
Speicherklasse 10 - Combustible liquids

MONOCLONAL ANTI-HNRNP-A1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) is a ribonucleoprotein, which functions as an RNA-binding protein. It can interact with both RNA and DNA, through its two nucleic acid-binding domains. It is proteolytically cleaved into a 196-amino acid protein called UP1 (unwinding protein 1). This protein retains the two parent nucleic acid-binding domains. It is one of the major RNA-binding proteins, and though it localizes to nucleus, it can shuttle to cytoplasm as well.

Biochem/physiol Actions

HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) functions in mRNA metabolism. It shuttles continuously between nucleus and cytoplasm and functions in several processes such as mRNA export, internal ribosome entry site (IRES)-mediated translation and mRNA stability. In humans, it acts as an auxiliary factor for the processing of a specific miRNA substrate by binding specifically to pri-miR-18a, the stem-loop precursor of miR-18a and regulating its Drosha-mediated processing. Defects in this gene are associated with multisystem proteinopathy and ALS (Amyotrophic lateral sclerosis 20). An alternatively spliced isoform of this protein is capable of controlling the splicing and replication of human immunodeficiency virus (HIV)-1.

MONOCLONAL ANTI-HNRNP-A1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MONOCLONAL ANTI-HNRNP-A1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 15)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Atlas antibodies --
order@atlasantibodies.com China 6586 58
Merck KGaA --
ordercn@merckgroup.com China 6394 58
Signalway Antibody LLC --
info@sabbiotech.com China 6243 58
shlmai 021-67680335 13052188602
sale1@shlmai.net China 9672 58
Fuzhou Weisen Biotechnology Co., Ltd. --
CHINA 259 58
Nanjing Weiwo Biotechnology Co., Ltd. --
CHINA 6423 58

  • Monoclonal Anti-hnRNP-A1 antibody produced in mouse
  • Anti-HNRPA1 (AB2) antibody produced in rabbit
  • Anti-hnRNP A1 (Ab-192) antibody produced in rabbit
  • Anti-HNRPA1 (AB1) antibody produced in rabbit
  • Anti-HNRNPA1 antibody produced in rabbit
  • MONOCLONAL ANTI-HNRNP-A1
  • Anti-heterogeneous nuclear ribonucleoprotein-A1
  • Anti-hnRNP-A1
  • Anti-HNRPA1
  • HNRPA1
  • FLI-2
  • HDP-1
  • Helix-destabilizing protein
  • Heterogeneous nuclear ribonucleoprotein A1
  • Anti-HNRPA1L3
  • Anti-MGC102835
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