EO 1428

321351-00-2

CAS-Nr.: 321351-00-2

Englisch Name:: EO 1428

Synonyma:: EO 1428;p38 MAPK Inhibitor VIII;p38 MAP Kinase Inhibitor VIII;(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone;Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-

CBNumber:: CB12455755

Summenformel:: C20H16BrClN2O

Molgewicht:: 415.71

MOL-Datei:: 321351-00-2.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 38

EO 1428 Eigenschaften

storage temp.: Store at +4°C

L?slichkeit: Soluble to 100 mM in DMSO and to 50 mM in ethanol

Aggregatzustand: Powder

Farbe: yellow

InChI: 1S/C20H16BrClN2O/c1-12-4-2-3-5-15(12)20(25)16-8-7-14(11-17(16)22)24-19-9-6-13(21)10-18(19)23/h2-11,24H,23H2,1H3

InChIKey: HDCLCHNAEZNGNV-UHFFFAOYSA-N

SMILES: Brc1cc(c(cc1)Nc2cc(c(cc2)C(=O)c3c(cccc3)C)Cl)N

Sicherheit

WGK Germany	WGK 1
Speicherklasse	11 - Combustible Solids

EO 1428 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

EO 1428 is a p38 MAP kinase inhibitor with high antiinflammatory activity.

Biologische Aktivit?t

Selective inhibitor of p38 α and p38 β 2 that displays no activity at p38 γ , p38 δ , ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF- α , IL-6, IL-1 β and IL-10 (IC 50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.

EO 1428 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

EO 1428 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 38)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4964	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24958	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	6000	58

p38 MAP Kinase Inhibitor VIII
EO 1428
(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone
p38 MAPK Inhibitor VIII
Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
321351-00-2
C20H16BrClN2O

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