Fatostatin A
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- CAS-Nr.
- 298197-04-3
- Englisch Name:
- Fatostatin A
- Synonyma:
- Fatostatin;CS-2596;Fatostatin A;Fatostatin HBr;Fatostatin A HBr;25B11 hydrobromide;Fatostatin HBr，125B-11;Fatostatin hydrobromide;Fatostatin A HydrobroMide;Fatostatin (125B11) HBr ，S8284
- CBNumber:
- CB12602999
- Summenformel:
- C18H19BrN2S
- Molgewicht:
- 375.33
- MOL-Datei:
- 298197-04-3.mol
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Fatostatin A Eigenschaften
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥10mg/mL
- Aggregatzustand
- powder
- Farbe
- light yellow to yellow
- InChI
- 1S/C18H18N2S.BrH/c1-3-4-16-11-15(9-10-19-16)18-20-17(12-21-18)14-7-5-13(2)6-8-14;/h5-12H,3-4H2,1-2H3;1H
- InChIKey
- RJCFNQZVFUMORB-UHFFFAOYSA-N
- SMILES
- [s]1c(nc(c1)c3ccc(cc3)C)c2cc(ncc2)CCC.Br
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| WGK Germany |
1 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Fatostatin A Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic mice. Cell permeable. Fatostatin A is used for the treatment and/or prevention of one or more metabolic disorders.
Allgemeine Beschreibung
Fatostatin is a non-sterol diarylthiazole derivative. It prevents insulin-induced adipogenesis and lowers the amounts of fatty acid, triglyceride and low-density lipoprotein. Fatostatin has anti tumor and antimitotic properties.
Biochem/physiol Actions
Fatostatin hydrobromide is an SREBP inhibitor. Fatostatin hydrobromide inhibits fat production and lowers glucose levels in mice by inhibiting SREBP (Sterol Regulatory Element Binding Proteins).
Fatostatin A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fatostatin A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 109)Lieferanten
- Fatostatin A
- 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine MonohydrobroMide
- Fatostatin A HydrobroMide
- 2-(2-propylpyridin-4-yl)-4-p-tolylthiazole hydrobromide
- 25B11 hydrobromide
- 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide
- Fatostatin hydrobromide
- Fatostatin A HBr
- Fatostatin HBr
- CS-2596
- Fatostatin hydrobromide - Fatostatin A hydrobromide | 125B11 hydrobromide
- Fatostatin - CAS 298197-04-3 - Calbiochem
- Fatostatin HBr，125B-11
- Golgi,ob/ob,inhibit,Fatostatin hydrobromide,prostate,SREBP-mediated,cancer,mice,insulin-induced,adipogenesis,Fatty Acid Synthase (FASN),gene,human,expression,Inhibitor,125B11
- Fatostatin, SREBP (Sterol regulatory binding protein) transcription factors activation.
- Fatostatin hydrobromide, 10 mM in DMSO
- Fatostatin (125B11) HBr ，S8284
- Pyridine, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-, hydrobromide (1:1)
- 4-[4-(4-methylphenyl)-2-thiazoleyl]-2-propylpyridinehydrobromoacidsalt
- Fatostatin
- 298197-04-3
- C18H18N2SHBr
- Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
- API
