LDN212854
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- CAS-Nr.
- 1432597-26-6
- Englisch Name:
- LDN212854
- Synonyma:
- CS-1202;LDN212854;BMP Inhibitor III;LDN-212854, >=98%;LDN-212854 ，S7147;LDN212854 USP/EP/BP;BMP INHIBITOR III;LDN212854;LDN 212854;LDN-212854 (This product is only available in Japan.);5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyriMidin-3-yl]quinoline;5-[6-[4-(Piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
- CBNumber:
- CB12684548
- Summenformel:
- C25H22N6
- Molgewicht:
- 406.48
- MOL-Datei:
- 1432597-26-6.mol
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LDN212854 Eigenschaften
- Dichte
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble1mg/mL, clear (warmed)
- Aggregatzustand
- powder
- pka
- 8.79±0.10(Predicted)
- Farbe
- white to beige
- InChI
- 1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2
- InChIKey
- BBDGBGOVJPEFBT-UHFFFAOYSA-N
- SMILES
- [n]21ncc(c2ncc(c1)c5ccc(cc5)N6CCNCC6)c3c4c(nccc4)ccc3
- CAS Datenbank
- 1432597-26-6
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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LDN212854 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, contains the pyrazolo[1,5-a]pyrimidine scaffold, acting as a novel and selective bone morphogenetic protein receptor (BMP) inhibitors. It is a COVID19-related research product.
Biochem/physiol Actions
LDN-212854 is also known as 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline. LDN-212854 prevents heterotopic ossification in an inducible mutant ALK2 (activin receptor-like kinase 2).
LDN212854 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
LDN212854 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 115)Lieferanten
- LDN212854
- Quinoline, 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-
- BMP Inhibitor III
- 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyriMidin-3-yl]quinoline
- 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline LDN 212854
- LDN 212854 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
- LDN-212854, >=98%
- CS-1202
- BMP INHIBITOR III;LDN212854;LDN 212854
- LDN-212854 (This product is only available in Japan.)
- 5-[6-[4-(Piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
- LDN212854 USP/EP/BP
- LDN-212854 ，S7147
- 1432597-26-6
- 1432587-26-6
- Inhibitors
