ACT-132577

1103522-45-7

CAS-Nr.: 1103522-45-7

Englisch Name:: ACT-132577

Synonyma:: Aprocitentan;N-Despropyl Macitentan;ACT-132577;Depropylmethacetin;Despropyl Macitentan;Macitentan ACT-132577;Macitentan Impurity 07;Macitentan ACT-132577-D4;D4-N-Despropyl Macitentan;Aprocitentan, 10 mM in DMSO

CBNumber:: CB12685914

Summenformel:: C16H14Br2N6O4S

Molgewicht:: 546.19

MOL-Datei:: 1103522-45-7.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 196

ACT-132577 Eigenschaften

Schmelzpunkt:: 139-141°C

Siedepunkt:: 705.0±70.0 °C(Predicted)

Dichte: 1.841±0.06 g/cm3(Predicted)

storage temp.: -20°C Freezer

L?slichkeit: Chloroform (Slightly, Heated), Methanol (Slightly, Heated)

Aggregatzustand: Solid

pka: 13.56±0.60(Predicted)

Farbe: White to Off-White

InChI: InChI=1S/C16H14Br2N6O4S/c17-11-3-1-10(2-4-11)13-14(24-29(19,25)26)22-9-23-15(13)27-5-6-28-16-20-7-12(18)8-21-16/h1-4,7-9H,5-6H2,(H2,19,25,26)(H,22,23,24)

InChIKey: DKULOVKANLVDEA-UHFFFAOYSA-N

SMILES: S(NC1C(C2=CC=C(Br)C=C2)=C(OCCOC2=NC=C(Br)C=N2)N=CN=1)(N)(=O)=O

Sicherheit

ACT-132577 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-Despropyl-macitentan, is an active metabolite which is part of a family of endothelin receptor antagonist that allows for treatment of pulmonary arterial hypertension (PAH)

ACT-132577 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ACT-132577 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 196)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Zhejiang Hengkang Pharmaceutical Co.Ltd.	+8615168202657	commercial@hengkangpharm.cn	China	42	58
Chongqing jooe co., ltd	+undefined86-15223382610	info@jooe.com	China	15976	58
Jinan Jianfeng Chemical Co., Ltd	+86-0531-88110457 +8615562555968	info@pharmachemm.com	China	311	58
Nanjing Dorra Pharmaceutical Technology Co., Ltd	+86-15951889564 +86-025-82232955	info@dorrapharma.com	China	29	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Shochem(Shanghai) Co.,Ltd	86-21-50800795	info@shochem.com	CHINA	288	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
ENBRIDGE PHARMTECH CO., LTD.	+8613812269233	tinayang@enbridgepharm.com	China	306	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58

ACT-132577
N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]sulfamide
5-(4-BROMOPHENYL)-4-[2-(5-BROMOPYRIMIDIN-2-YL)OXYETHOXY]-6-(SULFAMOYLAMINO)PYRIMIDINE
APROCITENTAN; ACT-132577; ACT 132577; ACT132577; DESPROPYL MACITENTAN
Despropyl Macitentan
Sulfamide, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-
Macitentan N-Despropyl Impurity
N-[5-(4-bromophenyl)-6-[2-(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl
Macitentan ACT-132577
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(sulfamoyl)pyrimidin-4-amine
Macitentan ACT-132577-D4
N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]aminosulfonamide
5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]-ethoxy]-4-pyrimidinyl]sulfamide
Macitentan Impurity 07
Despropyl Macitentan (COLD SHIPMENT REQUIRED)
N-(5-(4-Bromophenyl)-6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)pyrimidin-4-yl)sulfamide
N-(5-(4-Bromophenyl)-6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)pyrimidin-4-yl)sulfamide , Aprocitentan
Aprocitentan, 10 mM in DMSO
N - [5- (4-bromophenyl) -6- [2- [(5-bromo-2-pyrimidinyl) oxy] ethoxy] -4-pyrimidinyl] aminosulfonamide
Depropylmethacetin
D4-N-Despropyl Macitentan
N-Despropyl Macitentan (Aprocitentan)
Aprocitentan
N-Despropyl Macitentan
1103522-45-7
110-65-7
C16H14Br2N6O4S
APIS
API

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