(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

475473-26-8

CAS-Nr.: 475473-26-8

Englisch Name:: (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

Synonyma:: CORM-3;CORM-3, 10 mM in DMSO;Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium;Tricarbonylchloro(glycinato)ruthenium (II);(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium;(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium;Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-;inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)

CBNumber:: CB12717709

Summenformel:: C5H3ClNO5Ru

Molgewicht:: 293.6

MOL-Datei:: 475473-26-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 91

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Eigenschaften

storage temp.: -20°C

L?slichkeit: H2O: soluble20mg/mL, clear

Aggregatzustand: powder

Farbe: light yellow to dark yellow

Wasserl?slichkeit: Soluble to 100 mM in water

InChI: 1S/C2H5NO2.3CO.ClH.Ru/c3-1-2(4)5;3*1-2;;/h1,3H2,(H,4,5);;;;1H;/q;;;;;+2/p-2

InChIKey: BICHHHDSEZXKNN-UHFFFAOYSA-L

SMILES: [Ru+2].[Cl-].NCC(=O)[O-].O=[C].O=[C].O=[C]

Sicherheit

WGK Germany	3
Speicherklasse	11 - Combustible Solids

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H₂O₂-induced apoptosis using primary rabbit lens epithelial cells.

Biochem/physiol Actions

CORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 91)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16512	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30224	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28760	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-
Carbon monoxide releasing molecule 3
Tricarbonylchloro(glycinato)ruthenium (II)
Tricarbonylchloro(glycinato)ruthenium
inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium
CORM-3, 10 mM in DMSO
CORM-3
475473-26-8
C5H4ClNO5Ru
Inhibitors

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