Debio-1347 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CH5183284 is an orally available and selective FGFR (fibroblast growth factor receptor) inhibitor acting on FGFR 1, 2, and 3.

Synthese

The synthesis of Debio-1347 is as follows:
An aqueous solution (1.67 ml) of 4 M sodium hydroxide was added to an ethanol solution (17 ml) of [5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazol-4-yl]-(1-benzenesulfonyl-1H-indol-2-yl) methanone (87 mg). The resulting mixture was stirred at room temperature for 2 hours. The reaction mixture was poured into water. The resulting solid was collected by filtration, washed with water, and dried to give Debio-1347 (40 mg, 63%).

Debio-1347 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Debio-1347 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Dideu Industries Group Limited	+86-86-15536356810 +8617392712697	1022@dideu.com	China	28760	58
Chemia Biotechnology（Shanghai） Co., Ltd	+8613816753574	info@chemia-pharm.com	CHINA	311	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39039	58

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• Debio-1347
• FF284
• CH5183284 (Debio-1347)
• (5-amino-1-(2-methyl-3H-benzo[d]imidazol-5-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone
• CH5183284
• Debio-1347:CH5183284
• CH5183284;CH-5183284;CH 5183284
• CS-1637
• [5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazol-4-yl](1H-indol-2-yl)methanone
• Methanone, [5-amino-1-(2-methyl-1H-benzimidazol-6-yl)-1H-pyrazol-4-yl]-1H-indol-2-yl-
• DCH5183284
• CH-5183284 (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone
• CH5183284 (FF-284
• (5-Amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone
• 13C6]-Debio1347
• CH 518328
• Zoligratinib, 10 mM in DMSO
• Zoligratinib (Debio-1347)
• Zoligratinib
• 1265229-25-1
• Inhibitors
• API