AG 825 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

A selective ErbB2 inhibitor

Definition

ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

Biologische Aktivit?t

Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

AG 825 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

AG 825 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28760	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53803	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
Suzhou Chireach Biomedical Technology Co., Ltd.	0512-65856968	sales@chireach.com	China	59	70
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9658	60

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• TYRPHOSTIN AG 825
• TYRPHOSTIN C15
• AG 825
• 5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE
• 5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE
• 4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE
• 3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano- 2-Propenamide
• Tyrphostin C15, 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide
• AG 825 (Tyrphostin AG 825)
• (E)-3-[3-[(2-BENZOTHIAZOLYTHIO)METHYL]-4-HYDROXY-5-METHOXYPHENYL]-2-CYANO-2-PROPENAMIDE
• Zinc02572484
• AG 825 USP/EP/BP
• 2-Propenamide, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-
• AG 825 - CAS 149092-50-2 - Calbiochem
• 3-(3-((Benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide
• AG 825, ErbB2 inhibitor
• AG-825, 10 mM in DMSO
• 149092-50-2
• Cell Signaling and Neuroscience
• Cell Biology
• BioChemical
• Kinase/Phosphatase Biology
• Receptor Tyrosine Kinase Inhibitors
• Epidermal Growth Factor Receptor (EGFR)
• Protein Kinase