tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
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- CAS-Nr.
- 1201187-44-1
- Englisch Name:
- tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
- Synonyma:
- N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...;tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate;Upadacitinib Impurity 3;Upadacitinib Intermediate4;Upadacitinib intermediate2;Upadacitinib Intermediates;Intermediate of Upadacitinib (ABT-494);2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbama;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
- CBNumber:
- CB13102742
- Summenformel:
- C18H20N4O4S
- Molgewicht:
- 388.44
- MOL-Datei:
- 1201187-44-1.mol
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Eigenschaften
- Dichte
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- pka
- 9.45±0.43(Predicted)
- InChI
- InChI=1S/C18H20N4O4S/c1-12-5-7-13(8-6-12)27(24,25)22-10-9-14-16(22)19-11-15(20-14)21-17(23)26-18(2,3)4/h5-11H,1-4H3,(H,20,21,23)
- InChIKey
- NTMJGYRFMXFNIC-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NC1=CN=C2N(S(C3=CC=C(C)C=C3)(=O)=O)C=CC2=N1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.
Verwenden
Tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate, also known as upadacitinib intermediate 2, could be used in the synthesis and property studies of upadacitinib. This compound Often used as organic synthesis intermediates and pharmaceutical intermediates. It can be used in laboratory research processes and chemical production processes.
Lager
Sealed in dry, 2-8°C
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 279)Lieferanten
1201187-44-1()Verwandte Suche:
- tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
- Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester
- tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate
- Intermediate of Upadacitinib (ABT-494)
- 2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
- Upadacitinib intermediate2
- 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
- Upadacitinib Impurity 3
- Upadacitinib Intermediate4
- tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
- N-[5-[(4-Methylphenyl)sulfony!]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic, acid 1, 1-dimethylethyl ester
- Upadacitinib Intermediates
- 1,1-Dimethylethyl N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
- tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbama
- 5-toluenesulfonyl-5H-pyrrolo [2,3-B] pyrazine-2-aminoformic acid tert butyl ester
- tert-butyl 5-tosyl-5H-pyrrolo[2,3-blpyrazin-2-ylcarbamate
- N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...
- 1201187-44-1
