Dmt-2'fluoro-da(bz) amidite Chemische Eigenschaften,Einsatz,Produktion Methoden

Synthese

3-((Bis(diisopropylamine)phosphanyl)oxy)propanenitrile (6.42 g, 21.3 mmol, 6.77 mL, 1.8 eq) was added to a solution of N-(9-((2R,3R,4R,5R)-5-((bis(4- methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-9H- purine-6-yl)benzamide (8.0 g, 11.8 mmol, 1.0 eq) in DCM (42 mL) at 0 °C followed by DCI (2.24 g, 18.9 mmol, 1.6 eq). The mixture was warmed to 25 °C and stirred for 3 hours. Two parallel reactions were carried out. The combined remedies were then diluted with DCM (150 mL), the organic layer was washed with sat NaHCO3 solution (200 mL) and brine (100 mL), dried over Na2SO4, filtered and concentrated, the crude was purified by column chromatography to give Dmt-2'fluoro-da(bz) amidite (18.0 g, 18.5 mmol, 78.1% yield, 90% purity) as a white solid.

Lager

store at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year.

Dmt-2'fluoro-da(bz) amidite Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dmt-2'fluoro-da(bz) amidite Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +86-18055326116	sales1@nuowei-chem.com	China	1627	58
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
Allbiosyn Biotechnology Co.,Ltd.	+8618666985712	info@allbiosyn.com	China	295	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5745	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
NINGBOBENKANGJS PHARMTECHCO., LTD	+8615990591583 15990591583		CHINA	2029	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58

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• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoroadenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
• 5'-Dimethoxytrityl-N-Benzoyl-2'-fluoro-3'-[(2-cyanoethyl)-(N,Ndiisopropyl)]-phosphoramidite-deoxyadenosine
• Bz-2'-F-dA Phosphoramidite
• (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite, >97%
• N6-Benzoyl-5'-O-(4,4'-Dimethoxy trityl)-2'-deoxy-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diiso-propyl)]phosphoramidite
• 5'-DMT-2'-F-Bz-dA Phosphoramidite
• Dmt-2'fluoro-da(bz) amidite
• 2'-F-dA(Bz)-CE Phosphoramidite
• Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
• 2'-F-N6-Bz-dA phosphoramidite
• 2'-DEOXY-2'-FLUORO-N6Bz-ADENOSINE-3'-CE-PHOSPHORAMIDITE
• 2'-fluoro-N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-3'-CE-Phosphoramidite
• 5'-O-DMT-2'-Fluoro-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite
• 5'-O-DMT-2'-F-Benzoyl-Deoxyadenosine-CE Phosphoramidite
• DMT-2'-F-dA(bz) Phosphoramidite
• N6-Bz-5'-O-DMT-2'-fluoro-dA-CE
• 5'-O-DMT-2'-F-N6- Benzoyl-2'-Deoxy Adenosine -3’-Cyanoethyl Phosphoramidite
• 2'-Fluoro-N-Bz Adenosine Amidite
• N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-fluoro-2’-deoxyadenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
• DMTr-2'-F-dA(Bz)-3'-CE-Phosphoramidite
• 2’-F-dA(Bz) Amidite
• 2'-F-Bz-A Phosphoramidite
• 2'-F-Bz-dA-CE-Phosphoramidite
• 2'-F-dA(Bz)-CE-Phosphoramidite
• 2'-F-Bz-dA Phosphoramidite
• 2'-Fluoro-dA CEP
• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoroadenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
• (2R,3R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
• N6-Bz-2'-F-5'-O-DMT-2'-dA-3'-CE-Phosphoramidite
• 2'-F-dA(Bz)Phosphoramidite
• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluoroadenosine
• N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite
• Dmt-2''fluoro-da(bz) amidite
• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluoroadenosine
• 2'-F-Bz-A Phosphoramidite
• N6-Bz-5'-O-DMT-2'-Fluoro-dA-CE, 99%, ≤0.2%(K.F.)
• 2’-Fluoro-rABz Phosphoramidite, N6-Benzoyl-5'-O-DMT-2'-fluoro-2’deoxyadenosine-3'-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite,
• 2’-F-rA(N-Bz) CE Phosphoramidite
• 2’-F-rA(N-Bz) phosphoramidite
• N4-Bz-5’-O-DMTr-2’-deoxy-2’-fluoroadenosine-3’-CED phosphoramidite
• 2’-Fluoro-A(Bz)-3’-phosphoramidite
• 2'-F-dA(Bz)-3'-CE-phosphoramidite
• 5'-ODMT-2'-Fluoro-N-Bz Adenosine-3'-OCEPA
• DMT-2'-Fluoro-dA(Bz) Phosphoramidite
• DMT-2'-F-dA(Bz)-CE Phosphoramidite
• N6-Bz-5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-CE-Phosphoramidite
• 136834-22-5
• Amidite