1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE
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- CAS-Nr.
- 688348-33-6
- Englisch Name:
- 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE
- Synonyma:
- CAY10465;CAY10465 Exclusive;CAY 10465, 10 mM in DMSO;CAY10465;CAY-10465;CAY 10465;1,3-Dichloro-5-(4-(trifluoromethyl)styryl)benzene;1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE;1,3-dichloro-5-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}benzene;CAY-10465,AhR,CAY 10465,inhibit,Inhibitor,Aryl Hydrocarbon Receptor;Benzene, 1,3-dichloro-5-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-
- CBNumber:
- CB1397651
- Summenformel:
- C15H9Cl2F3
- Molgewicht:
- 317.13
- MOL-Datei:
- Mol file
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1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Eigenschaften
- Siedepunkt:
- 361.2±42.0 °C(Predicted)
- Dichte
- 1.378±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- L?slichkeit
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .5 mg/ml; Ethanol: 20 mg/ml
- Aggregatzustand
- A crystalline solid
- Farbe
- White to off-white
Sicherheit
1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
The aryl hydrocarbon receptor (AhR) is a ligand-
dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. CAY10465 is an analog of resveratrol acting as a potent and selective AhR agonist, with a K
i of 0.2 nM. CAY10465 is inactive as a ligand for the estrogen receptor even at 100 μM.
Verwenden
(E)-1-[4-(Trifluoromethyl)phenyl]-2-(3,5-dichlorophenyl)ethene is a stilbene derivative of resveratrol and a selective aryl hydrocarbon receptor agonist.
1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 59)Lieferanten
- CAY10465
- 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE
- 1,3-dichloro-5-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}benzene
- CAY10465 Exclusive
- CAY10465;CAY-10465;CAY 10465
- CAY-10465,AhR,CAY 10465,inhibit,Inhibitor,Aryl Hydrocarbon Receptor
- Benzene, 1,3-dichloro-5-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-
- 1,3-Dichloro-5-(4-(trifluoromethyl)styryl)benzene
- CAY 10465, 10 mM in DMSO
- 688348-33-6
