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SR 2595

SR 2595 Struktur
1415252-61-7
CAS-Nr.
1415252-61-7
Englisch Name:
SR 2595
Synonyma:
SR 2595;SR2595 >=98% (HPLC);2-[4-[[5-[[(1S)-1-(4-tert-Butylphenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]phenyl]benzoic acid;4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylicacid;[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-
CBNumber:
CB14666849
Summenformel:
C37H38N2O3
Molgewicht:
558.71
MOL-Datei:
1415252-61-7.mol

SR 2595 Eigenschaften

Siedepunkt:
785.4±60.0 °C(Predicted)
Dichte
1.13±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≤5mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
pka
3.87±0.36(Predicted)
Farbe
white to faint brown
InChIKey
WKDKAVKAQXVFJV-DEOSSOPVSA-N
SMILES
O=C(C(C=C1)=CC2=C1N(C(C)=C2C)CC(C=C3)=CC=C3C4=C(C(O)=O)C=CC=C4)N[C@H](C(C=C5)=CC=C5C(C)(C)C)C

Sicherheit

WGK Germany  WGK 3
Speicherklasse 11 - Combustible Solids

SR 2595 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

SR 2595 is an inverse agonist of PPARγ (IC50 = 30 nM) that represses both transactivation in a promoter:reporter assay and expression of the adipogenic marker fatty acid-binding protein 4 in differentiating murine preadipocytes. Repression of PPARγ with SR 2595 promotes osteogenesis, as measured by calcium phosphatase deposition, in cultured human mesenchymal stem cells (MSCs). SR 2595 also increases expression of bone morphogenetic proteins BMP2 and BMP6 in MSCs.

SR 2595 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


SR 2595 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 26)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
BOC Sciences 16314854226
info@bocsci.com United States 9923 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44909 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310 15002144251
marketing@tsbiochem.com China 24958 58
Hubei Aiputi Bioengineering Co., Ltd. 17762444226
d17762444226@163.com China 2402 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11972 58
Cayman Chemical Company --
sales@caymanchem.com China 6838 58
Merck KGaA --
ordercn@merckgroup.com China 6394 58

  • SR 2595
  • SR2595 >=98% (HPLC)
  • [1,1'-Biphenyl]-2-carboxylic acid, 4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-
  • 4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylicacid
  • 2-[4-[[5-[[(1S)-1-(4-tert-Butylphenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]phenyl]benzoic acid
  • 1415252-61-7
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