CINALUKAST

128312-51-6

CAS-Nr.: 128312-51-6

Englisch Name:: CINALUKAST

Synonyma:: Ro 24-591;RO 24-5913;CINALUKAST;C·Nalukast;2,2-Diethyl-N-[3-[(E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]succinamidic acid;(E)-4-[[3-(2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL)PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID;4-[[3-[(1E)-2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL]PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID;Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]aMino]-2,2-diethyl-4-oxo-;Ro 24-5913, (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid

CBNumber:: CB1486281

Summenformel:: C23H28N2O3S

Molgewicht:: 412.55

MOL-Datei:: 128312-51-6.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 50

CINALUKAST Eigenschaften

storage temp.: 2-8°C

L?slichkeit: DMSO: >10 mg/mL

Aggregatzustand: Powder

Farbe: off-white

InChIKey: BZMKNPGKXJAIDV-VAWYXSNFSA-N

SMILES: CCC(CC)(CC(=O)Nc1cccc(\C=C\c2nc(cs2)C3CCC3)c1)C(O)=O

Sicherheit

S-S?tze:	22-24/25
WGK Germany	3
Speicherklasse	11 - Combustible Solids

CINALUKAST Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Definition

ChEBI: 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in th human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.

Biologische Aktivit?t

Potent, selective CysLT 1 (LTD 4 ) leukotriene receptor antagonist (IC 50 = 6.4 nM). Inhibits LTD 4 -induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol.

CINALUKAST Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CINALUKAST Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 50)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19956	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15402	60
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12335	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4784	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Chengdu Huachun Technology Co., Ltd	400-1166-196 15982826727	cdhxsj@163.com	China	14603	60

(E)-4-[[3-(2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL)PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID
CINALUKAST
RO 24-5913
4-[[3-[(1E)-2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL]PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID
Ro 24-591
Ro 24-5913, (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
2,2-Diethyl-N-[3-[(E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]succinamidic acid
Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]aMino]-2,2-diethyl-4-oxo-
C·Nalukast
128312-51-6
C23H28N2O3S
Intermediates & Fine Chemicals
Pharmaceuticals

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