(2-Phenylethyl)hydrazin-sulfat(1:1)
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- CAS-Nr.
- 156-51-4
- Bezeichnung:
- (2-Phenylethyl)hydrazin-sulfat(1:1)
- Englisch Name:
- Phenelzine Sulfate
- Synonyma:
- PHENELZINE SULFATE SALT;Phenelzine Sulfate (1517006);wl7;p1531;S-1544;ep-411;kalgan;alazin;N-1544A;mao-rem
- CBNumber:
- CB1719066
- Summenformel:
- C8H14N2O4S
- Molgewicht:
- 234.27
- MOL-Datei:
- 156-51-4.mol
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(2-Phenylethyl)hydrazin-sulfat(1:1) Eigenschaften
- Schmelzpunkt:
- 166.5-167.5 °C
- storage temp.
- 2-8°C
- L?slichkeit
- Freely soluble in water; practically insoluble in ethanol (96%) and in ether .
- Aggregatzustand
- A solid
- Farbe
- White to off-white
- Biologische Quelle
- synthetic
- Wasserl?slichkeit
- water: 50mg/mL, clear to slightly hazy, colorless to faintly yellow
- Merck
- 13,7300
- Major Application
- pharmaceutical (small molecule)
- InChI
- InChI=1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)
- InChIKey
- RXBKMJIPNDOHFR-UHFFFAOYSA-N
- SMILES
- C1(CCNN)C=CC=CC=1.S(=O)(=O)(O)O
- CAS Datenbank
- 156-51-4
- IARC
- 3 (Vol. 24, Sup 7) 1987
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| RIDADR |
UN 2811 6.1/PG 3 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
MV8750000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
2928002500 |
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| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications |
Acute Tox. 3 Oral |
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| Toxizit?t |
LD50 orally in mice: 156 mg/kg (Gylys) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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(2-Phenylethyl)hydrazin-sulfat(1:1) Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Chemische Eigenschaften
A white powder or pearly platelets.
Verwenden
Phenelzine Sulfate is a hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidep ressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.
Allgemeine Beschreibung
Phenelzine sulfate, 2-(phenylethyl)hydrazine sulfate(Nardil), is an effective antidepressant agent. A mechanismbasedinactivator, it irreversibly inactivates the enzyme orits cofactor, presumably after oxidation to the diazine,which can then break up into molecular nitrogen, a hydrogen atom, and a phenethyl free radical. The latter would bethe active species in irreversible inhibition.
Sicherheitsprofil
Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: wakefulness, blood pressure lowering, constipation, hepatitis, fibrous hepatitis. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. Used as a drug for the treatment of depression. When heated to decomposition it emits very toxic fumes of SOx and NOx.
(2-Phenylethyl)hydrazin-sulfat(1:1) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(2-Phenylethyl)hydrazin-sulfat(1:1) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 123)Lieferanten
156-51-4((2-Phenylethyl)hydrazin-sulfat(1:1))Verwandte Suche:
- (2-Phenylethyl)hydrazine dihydrogen sulfate
- Phenelzine Sulfate (200 mg)
- S-1544
- N-1544A
- HYDRAZINE,(2-PHENYLETHYL)-,SULPHATE
- BETA-PHENYLETHYLHYDRAZINESULPHATE
- 3-PHENYLETHYLHYDRAZINESULPHATE
- phenelzine hydrogen sulphate
- wl7
- phenylethylhydrazinesulphate
- fenelzin
- felazine
- estinerval
- ep-411
- beta-phenylethylhydrazinesulfate
- beta-phenylethylhydrazinehydrogensulphate
- beta-phenylethylhydrazinedihydrogensulfate
- phenylethylhydrazinedihydrogensulphate
- phenline
- PHENYLETHYLHYDRAZINE SULFATE
- PHENELZINE SULFATE
- 2-phenylethylhydrazinesulphate
- 2-phenylethylhydrazinehydrogensulphate
- 2-phenylethylhydrazinedihydrogensulphate
- 1-hydrazino-2-phenylethanehydrogensulphate
- (2-phenylethyl)-hydrazinsulfate(1:1)
- 2-PHENYLETHYLHYDRAZINE SULFATE
- Phenethylhydrazine Sulfate
- Phenelzine Hydrogen Sulfate
- Phenelzine Dihydrogen Sulfate
- Phenelzine Bisulfate
- NSC 170957
- 2-Phenethylhydrazine sulfate
- (β-Phenylethyl)hydrazine dihydrogen sulfate
- phenethyl-hydrazinsulfate(1:1)
- phenethylhydrazinesulphate
- phenethylhydrazinesulfate(1:1)
- phenelzinesulphate
- phenelzinebisulphate
- phenelzineacidsulfate
- phelazin
- p1531
- nardelzine
- mao-rem
- kalgan
- Acid sulfate
- alacine
- alazin
- alazine
- Phenelzine Sulfate USP/EP/BP
- henelzine Sulfate
- inhibit,Inhibitor,Phenelzine sulfate,MAO,Monoamine Oxidase,Phenelzine
- Phenelzine-d5 sulfate (phenyl-d5) in methanol
- Phenelzine sulfate, 10 mM in DMSO
- Phenelzine Sulfate (1517006)
- PHENELZINE SULFATE SALT
- 156-51-4
- 56-51-4
