SE 175 Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-
donors
in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC
50 of 20 μM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.
SE 175 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
