N-Boc-4-piperidinemethanol
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- CAS-Nr.
- 123855-51-6
- Englisch Name:
- N-Boc-4-piperidinemethanol
- Synonyma:
- TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;1-BOC-4-PIPERIDINEMETHANOL;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL
- CBNumber:
- CB2100290
- Summenformel:
- C11H21NO3
- Molgewicht:
- 215.29
- MOL-Datei:
- 123855-51-6.mol
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N-Boc-4-piperidinemethanol Eigenschaften
- Schmelzpunkt:
- 78-82 °C (lit.)
- Siedepunkt:
- 308.0±15.0 °C(Predicted)
- Dichte
- 1.059±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- soluble in Methanol
- Aggregatzustand
- Powder
- pka
- 14.94±0.10(Predicted)
- Farbe
- White to brown
- InChI
- InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
- InChIKey
- CTEDVGRUGMPBHE-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(CO)CC1
- CAS Datenbank
- 123855-51-6(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| S-S?tze: |
24/25 |
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| WGK Germany |
3 |
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| HazardClass |
IRRITANT |
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| HS Code |
29339900 |
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| Speicherklasse |
13 - Non Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P332+P313 |
Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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N-Boc-4-piperidinemethanol Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White to light brown solid
Verwenden
N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.
Application
N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.
Allgemeine Beschreibung
N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (
t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-
tert-butyldicarbonate.
N-Boc-4-piperidinemethanol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-Boc-4-piperidinemethanol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 467)Lieferanten
123855-51-6()Verwandte Suche:
- 1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE
- 1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
- 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
- TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
- N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL
- N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE
- N-T-BUTOXYCARBONYL-4-PIPECOLINOL
- N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL
- N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
- N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
- 1-Boc-4-(hydroxymethyl)piperidine
1-Boc-4-piperidinemethanol
1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
- N-Boc-4-piperidineMe
- 1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet
- N-Boc-4-piperidinemethanol ,97%
- N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol
- 4-(Hydroxymethyl)piperidine, N-BOC protected 97%
- 1-Boc-4-(hydroxymethyl)-p...
- tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
- t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate
- tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate
- N-BOC-piperidin-4-Methanol
- N-Boc-4-piperidineMethanol, 95+%
- N - bok - 4 - piperidine Methanol
- 1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol
- N-Boc-4-piperidinemethanol 97%
- 1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate
- n-tert-butyloxycarbonyl-4-piperidinemethanol
- N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE
- N-BOC-4-HYDROXYMETHYLPIPERIDINE
- N-BOC-4-PIPERIDINEMETHANOL
- 1-N-Boc-4-piperidinemethanol
- tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate
- 1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL
- (1-Boc-Piperidin-4-yl)methanol
- 1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL
- N-BOC-4-HYDROXYMETHYLPIPERDINE
- N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 %
- 1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester
- 1-Boc-4-Hyroxymethyl-Piperidine
- 4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine
- BUTTPARK 75\50-52
- BOC-PIC(4)-OL
- BOC-ISONICOT(HEXAHYDRO)-OL
- 4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE
- 4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- 4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED
- 1-BOC-4-(HYDROXYMETHYL)PIPERIDINE
- tert-Butyl 4-(hydroxymethyl)-1
- 1-(tert-Butoxycarbonyl)-4-piperidinemethanol >
- Boc-4-Piperidine methanol
- N-Boc-4-piperidinyl alcohol
- N-Boc 4-piperdine methanol
- N-Boc-4-piperidinemethanol 123855-51-6
- N-BOC-piperidine-4-methanol
- 4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester
- N-Boc-4-piperidinemethanol
- N-Boc-4-piperidinecarbinol
- 1-BOC-4-PIPERIDINEMETHANOL
