Anti-Inflammatory Chemische Eigenschaften,Einsatz,Produktion Methoden
Originator
Alflorone Acetate,MSD,US,1954
Manufacturing Process
Hydrocortisone acetate is first reacted with phosphorus oxychloride in pyridine
to give the corresponding olefin. Then a sequence consisting of hypobromous
acid addition, ring closure to the epoxide and ring opening with hydrogen
fluoride gives fludrocortisone acetate. Preparation of a crystalline product is
described then in US Patent 2,957,013.
Therapeutic Function
9-Fluoro-11β,17,21-trihydroxy-pregn-4-ene-3,20-dione
acetate
Anti-Inflammatory Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
