Collagenase
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- CAS-Nr.
- 9001-12-1
- Bezeichnung:
- Collagenase
- Englisch Name:
- Collagenase
- Synonyma:
- FIBROBLAST;Collagenase IV;Collagenase II;Collagenase clostridium histolyticum;D12;Santyl;INTERSTITIAL;Collagenase A;COLLAGENASE TYPE XI;Clostridiopeptidase A
- CBNumber:
- CB2112176
- Summenformel:
- C60H100N2
- Molgewicht:
- 849.4494
- MOL-Datei:
- 9001-12-1.mol
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Collagenase Eigenschaften
- storage temp.
- -20°C
- L?slichkeit
- Soluble in aqueous buffers.
- Aggregatzustand
- powder
- Farbe
- light brown
- PH
- 7.0
- Biologische Quelle
- Clostridium histolyticum
- Wasserl?slichkeit
- water: soluble
- Merck
- 2481
- Specific Activity
- 0.5-5.0FALGPA units/mg solid
- InChIKey
- YRQNKMKHABXEJZ-UVQQGXFZSA-N
- CAS Datenbank
- 9001-12-1
- EPA chemische Informationen
- Collagenase (9001-12-1)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
36/37/38-42 |
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| S-S?tze: |
22-24-26-36/37 |
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| WGK Germany |
1 |
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| F |
10-21 |
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| TSCA |
TSCA listed |
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| HS Code |
3507907000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
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P261, P285, P304+P341, P342+P311,P501 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P284 |
Atemschutz tragen. |
| P342+P311 |
Bei Symptomen der Atemwege: GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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Collagenase Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R42:Sensibilisierung durch Einatmen m?glich.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24:Berührung mit der Haut vermeiden.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Verwenden
This collagenase has been tested with cell lines to verify the product is not cytotoxic. Collagenase is typically used to digest the connective components in tissue samples to liberate individual cells. The concentration for cartilage dispersal is 1-2 mg/ml, but literature searches should be performed for species specific and/or tissue specific concentrations.
Definition
A rare proteinase that catalyzes the hydrolysis of collagen. Collagenase activity has been demonstrated
in several venoms of crotalid and viperid snakes and
it occurs in certain species of clostridium.
Allgemeine Beschreibung
Collagenase from
Clostridium histolyticum comprises of collagenases G and H. Collagenase has N-terminal activator domain and C-terminal peptidase domain. The collagen binding domains (CBD) and polycystic kidney disease-like (PKD-like) domain resides in the peptidase domain. The collagenase module undergoes structural changes upon calcium binding.
l?uterung methode
Collagenase is purified by using N-ethylmaleimide to activate the enzyme, and wheat germ agglutinin-agarose affinity chromatography [Callaway et al. Biochemistry 25 4757 1986].
Collagenase Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Collagenase Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 495)Lieferanten
9001-12-1(Collagenase)Verwandte Suche:
- COLLAGENASE TYPE X
- collagenase crude type ia cell culture*tested
- collagenase F. clostridium histolyticum
- collagenase from achromobacter iophagus
- collagenase sterile filtered type vii-S
- collagenase type I-S
- Matrix metalloprotease-1
- Metallocollagenase
- Soycollagestin
- (VIAL) COLLAGENASE NB1 GMP GRADE
- COLLAGENASE NB4 FROM CL. HIST.STANDARD GRADE
- COLLAGENASE NB1 FROM CL. HIST.PREMIUM GRADE
- COLLAGENASE NB 8 FROM CL. HISTOLYTICUMBROAD RANGE
- COLLAGENASE NB6 FROM CL. HISTOLYTICUMGMP GRADE
- COLLAGENASE NB 5 FROM CL. HISTOLYTICUMSTERILE GRADE
- COLLAGENASE N REFERENCE CONTENT
- COLLAGENASE N REFERENCEIDENTITY
- COLLAGENASE NB 4G PROVED GRADE
- Collagenase from Clostridium histolyticum,Clostridiopeptidase A
- Collagenase,Type-III,from Clostridium histolyticum
- Collagenase V
- Collagenase from Clostridium histolyticum,lyophil.
- Recombinant Collagenase G >95%
- Recombinant Collagenase H >95%
- Recombinant Collagenase H/G >70%
- Recombinant Collagenase H/G >95%
- Collagenase NB 4G Proved Grade froM ClostridiuM histolyticuM crude
- Collagenase froM ClostridiuM histolyticuM(Purified)
- Anti-MMP1 (Cleaved-Phe100) antibody produced in rabbit
- collagenase type vii
- Collagenase, Paralithodes camtschatica Hepatopancreas
- Collagenase, Type II, Clostridium histolyticum
- Collagen-Peptide
- COLLAGENASE TYPE IA-S CELL CULTURE TESTED
- COLLAGENASE SIGMA BLEND TYPE N
- COLLAGENASE SIGMA BLEND TYPE L
- COLLAGENASE TYPE XI-S CELL CULTURE TESTED
- COLLAGENASE TYPE VII-S CELLCULTURE TESTE D
- COLLAGENASE TYPE III FRACTION A
- COLLAGENASE FROM CLOSTRIDIUM HISTOLYTICUM, TYPE IV
- COLLAGENASE F. CLOSTRIDIUM HISTOLYTICUM POWD.0.15-0.4 U/MG*
- COLLAGENASE FROM CLOSTRIDIUM HISTOLY-TIC UM, ~0.5-2 U/MG
- COLLAGENASE HIGH PURITY TYPE VII CELLCUL TURE TESTE
- COLLAGENASE SIGMA BLEND TYPE F
- COLLAGENASE SIGMA BLEND TYPE H
- COLLAGENASE FROM CLOSTRIDIUM HISTOLYTICUM, TYPE VIII
- COLLAGENASE TYPE IV-S
- COLLAGENASE FROM CLOSTRIDIUM HISTOLY-TIC UM, ~0.1 U/MG
- COLLAGENASE STERILE FILTERED TYPE XI-S
- COLLAGENACOLLAGENASE FROM CLOSTRIDIUM HISTOLYTICUM, TYPE IA, FOR GENERAL USE
- COLLAGENASE FROM CLOSTRIDIUM HISTOLYTICUM, TYPE II
- COLLAGENASE CRUDE TYPE XI CELL CULTURETE STED
- COLLAGENASE TYPE S
- COLLAGENASE TYPE IA-S
- COLLAGENASE TYPE V-S
- CollagenaseFormIiExClostridiumHistolyt-
- CollagenaseFormIExClostridiumHistolyti-
- COLLAGENESE
