Methylophiopogonanone A
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- CAS-Nr.
- 74805-92-8
- Englisch Name:
- Methylophiopogonanone A
- Synonyma:
- Methylophiopogonanone A;R-Methylophiopogonanone A;8-Methylophiopogonanone A;Methylophiopogonanone A -RM;Methylophiopogonanone A (MO-A);Methylophiopogonanone A, 10 mM in DMSO;Methylophiopogonanone A(R-Methylophiopogonanone A);3-(benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one;(R)-3-(Benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one;(3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one
- CBNumber:
- CB21267822
- Summenformel:
- C19H18O6
- Molgewicht:
- 342.34
- MOL-Datei:
- 74805-92-8.mol
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Methylophiopogonanone A Eigenschaften
- Siedepunkt:
- 580.1±50.0 °C(Predicted)
- Dichte
- 1.410
- storage temp.
- 2-8°C
- L?slichkeit
- Soluble in chloroform and methanol;
- Aggregatzustand
- powder
- pka
- 8.24±0.40(Predicted)
- Farbe
- Light yellow
- Wasserl?slichkeit
- insoluble in water
- InChI
- 1S/C19H18O6/c1-9-16(20)10(2)19-15(17(9)21)18(22)12(7-23-19)5-11-3-4-13-14(6-11)25-8-24-13/h3-4,6,12,20-21H,5,7-8H2,1-2H3/t12-/m1/s1
- InChIKey
- BXTNNJIQILYHJB-GFCCVEGCSA-N
- SMILES
- O=C1[C@H](CC2=CC=C(OCO3)C3=C2)COC4=C(C)C(O)=C(C)C(O)=C41
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Methylophiopogonanone A Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Methylophiopogonanone A is a homoisoflavonoid that has been found in
O. japonicus roots and has diverse biological activities. It increases the uptake of rosuvastatin (Item Nos.
12029 |
18813) and atorvastatin in HEK293T cells expressing human organic anion transporting polypeptide 1B1 (OATP1B1; EC
50s = 11.33 and 6 μM, respectively). Methylophiopogonanone A scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals in cell-free assays.
In vivo, methylophiopogonanone A (10 mg/kg) decreases body weight gain and reduces serum and hepatic lipid levels in a rat model of high-fat diet-induced hyperlipidemia. It also reduces infarct size and myocardial apoptosis in mouse model of ischemia-reperfusion injury induced by transient occlusion of the left anterior descending coronary artery.
Methylophiopogonanone A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methylophiopogonanone A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 190)Lieferanten
74805-92-8()Verwandte Suche:
- Methylophiopogonanone A
- Methylophiopogonanone A(R-Methylophiopogonanone A)
- 8-Methylophiopogonanone A
- (3R)-3-(1,3-Benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-4H-1-benzopyran-4-one
- R-Methylophiopogonanone A
- Methylophiopogonanone A (MO-A)
- (3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one
- 4H-1-Benzopyran-4-one, 3-(1,3-benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-, (3R)-
- 3-(benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one
- Methylophiopogonanone A -RM
- Methylophiopogonanone A, 10 mM in DMSO
- (R)-3-(Benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one
- 74805-92-8
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
