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Calcitonin (Lachs)

Calcitonin salmon Struktur
47931-85-1
CAS-Nr.
47931-85-1
Bezeichnung:
Calcitonin (Lachs)
Englisch Name:
Calcitonin salmon
Synonyma:
Salcatonin;SALMON;salmoncalcitonin-(i-32);Salmotonin;Salmon Calcium;Thyrocalcitonin;CALCITONIN, SALMON;tz-ct;calcimar;cibacalcin
CBNumber:
CB2127316
Summenformel:
C145H240N44O48S2
Molgewicht:
3431.85
MOL-Datei:
47931-85-1.mol

Calcitonin (Lachs) Eigenschaften

Schmelzpunkt:
>222oC (dec.)
Dichte
1.54±0.1 g/cm3(Predicted)
storage temp. 
−20°C
L?slichkeit
0.05 M acetic acid: 1 mg/mL, clear, colorless
Aggregatzustand
powder
Farbe
White to Off-White
Wasserl?slichkeit
Soluble in water at 1mg/ml
Merck 
13,1642
Sequenz
H-[Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2,(Disulfide bridge: Cys1-Cys7)
InChIKey
IYTKRMFJECGBRF-LXQLIYPUSA-N
CAS Datenbank
47931-85-1(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
S-S?tze: 22-24/25
WGK Germany  3
RTECS-Nr. EV8000000
3-10
HS Code  2937190000
Speicherklasse 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Bildanzeige (GHS) Skull and Crossbones (GHS06)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit

Calcitonin (Lachs) Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Calcitonin is a single-chain polypeptide consisting of 32 amino acid residues. Calcitonins as obtained from different species are identical at seven of the first nine residues, contain Gly at position 28, and all terminate with Pro-NH2. The C-terminal proline amide (ProNH2) is very important for the biological function of CT, as is the disulfide bridge between Cys residues at positions 1 and 7. In contrast, the residues from 10 through 27 can be varied and seem to influence CT's potency as well as its duration of action. Salmon CT differs from human CT at 16 amino acid residues.

Chemische Eigenschaften

White or almost white powder.

Verwenden

Calcitonin salmon can be used for calcitonin receptor/cAMP assay for assessing the presence of calcitonin receptors expressed by TRAP+ cells.The product can also be used as a test compound for studying as well as comparing the impact of calcitonin gene related peptide (CGRP) and salmon calcitonin (sCT) on gastric mucosal barrier in rats exposed to cold + restraint stress (CRS).

Clinical Use

Only salmon CT is commercially available for medical use, because on a weight basis, it is approximately 45-fold more potent than human CT. Salmon CT, in parenteral form, is approved for treating Paget's disease of bone (generally seen in older persons; involves increased bone resorption and softening of bones), postmenopausal osteoporosis, and hypercalcemia of malignancy (multiple myeloma or advanced breast carcinoma). Salmon CT also is available in a nasal spray formulation, which is used exclusively in the treatment of postmenopausal osteoporosis.

Calcitonin (Lachs) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Calcitonin (Lachs) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 453)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Getian Industrial Co., LTD
+86-15373193816
mike@ge-tian.com China 269 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599
info@molchanges.com China 5218 58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.
+8615051830413
sales.njleonbiotech@gmail.com China 5482 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823
admin@guyunchem.com China 615 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+86-15350851019; +8615350851019
admin@86-ss.com China 999 58
Adachibio Inc.
+81-8027837258; +8108027837258
sales@adachibio.com Japan 938 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
Rixing Chemical CO.,LTD
+86-13237129059 -13237129059
sales@rixingchemi.com CHINA 229 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60

47931-85-1(Calcitonin (Lachs))Verwandte Suche:


  • salmoncalcitonini
  • tz-ct
  • Salmon Calcitonin Acetate
  • CalcitoninAcetate
  • M.W. 3431.90 C145H240N44O48S2
  • Calcitoran
  • Calcitonin Acetate,form Salmon
  • H-[Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2
  • Salcitonin Acetate
  • calcimar
  • cibacalcin
  • salmoncalcitonin
  • CALCITONIN (SALMON I)
  • CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2
  • CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2 (DISULFIDE BRIDGE: 1-7)
  • CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2
  • CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2 SALMON
  • H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2
  • H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2 (DISULFIDE BRIDGE: 1-7)
  • H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2, (DISULFIDE BOND)
  • THYROCALCITONIN SALMON
  • CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2(DISULFIDE BRIDGE CYS1-CYS7)
  • Salcitonin
  • Calcitonin Salmon (20 mg) (COLD SHIPMENT REQUIRED)
  • Salcitonin Acetate(SalMon Calcitonin)
  • Salcatonin, SalMon Calcitonin, Thyrocalcitonin (salMon)
  • SalMon Calcitonin Aceta
  • H-CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-
  • Calcitonin (salMon) xAcetate
  • H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 acetate salt (Disulfide bond)
  • Salcitonin/Calcitonin
  • Calcitonin(Salmone) Acetate
  • Calcitonin salmon Acetate
  • Calcitonin, salmon synthetic
  • CALCITONIN SALMON 250 UG
  • Salmon Calcitonin Acetate, ≥97% (HPLC)
  • Salcatonin for Injection 
  • Calcitonin Salmon RS
  • Calcitonin?(Salmon) impurity
  • Cyclic (1→7)-disulfide L-Cysteinyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyros
  • Salmon calcitonin USP/EP/BP
  • Calcitonin salmon USP/EP/BP
  • Salcatonin,Calcitonin (Salmon)
  • Calcitonin (salmon) (C0200000)
  • Calcitonin Salmon (COLD SHIPMENT REQUIRED) (1086200)
  • Calcitonin salmon/Thyrocalcitonin
  • Salmon Calcitonin Impurities
  • Calcitonin Salmon (40 mg) (COLD SHIPMENT REQUIRED)
  • CALCITONIN, SALMON
  • SALMON
  • Salmotonin
  • Salmon Calcium
  • Salcatonin
  • salmoncalcitonin-(i-32)
  • Thyrocalcitonin
  • 47931-85-1
  • C145H240N44O48S2
  • Cell Biology
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