(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT

81496-19-7

CAS-Nr.: 81496-19-7

Englisch Name:: (4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT

Synonyma:: AH23848 CALCIUM SALT;AH23848 hemicalcium salt;COFQPJQSNPAAKY-LCCMWPRESA-M;(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT;(4Z)-7-[(rel-1S,2S,5R)-5-((1,1′-Biphenyl-4-yl)methoxy)-2-(4-morpholinyl)-3-oxocyclopentyl]- 4-heptenoic acid hemicalcium salt

CBNumber:: CB2134383

Summenformel:: C29H37CaNO5

Molgewicht:: 519.7

MOL-Datei:: Mol file

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 22

(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT Eigenschaften

storage temp.: -20°C

L?slichkeit: DMSO: 18 mg/mL at ≤60 °C

Aggregatzustand: solid

Farbe: off-white

InChIKey: JDEBIDDIERGZQY-XVFRBOAOSA-L

SMILES: O=C(C[C@@H](OCC1=CC=C(C2=CC=CC=C2)C=C1)[C@H]3CC/C=C\CCC(O[Ca]OC(CC/C=C\CC[C@@H]4[C@H](OCC5=CC=C(C6=CC=CC=C6)C=C5)CC([C@H]4N7CCOCC7)=O)=O)=O)[C@H]3N8CCOCC8

Sicherheit

WGK Germany	3
Speicherklasse	11 - Combustible Solids

(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

AH23848 has been used as an prostaglandin E2 receptor 4 (EP4) receptor antagonist to study its effect on cAMP accumulation in monocrotaline (MCT28d) rat pulmonary arterial smooth muscle cells (PASMCs) and human T cell enriched peripheral blood mononuclear cells (PBMC). It has also been used to study its effect on the expressions of collagen-I, metalloproteinase (MMP-1), MMP-3, and EP4 gene expression in human tendon fibroblasts following interleukin (IL)-1β treatment.

Biochem/physiol Actions

AH23848 regulates nitric oxide (NO) production and reduces endogenous cAMP accumulation. This is carried out by declination of inducible nitric oxide synthase (iNOS) gene expression and acceleration of iNOS protein degradation in glomerular mesangial cells.

(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4784	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
amyjet	4006800868;027-59626688 18371453821;18771149750	sales@amyjet.com	China	2917	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11972	58
Cayman Chemical Company	--	sales@caymanchem.com	China	6838	58
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58
Santa Cruz Biotechnology Inc	--	scbt@scbt.com	China	6594	58

(4Z)-7-[(REL-1S,2S,5R)-5-((1,1'-BIPHENYL-4-YL)METHOXY)-2-(4-MORPHOLINYL)-3-OXOCYCLOPENTYL]-4-HEPTENOIC ACID CALCIUM SALT
AH23848 CALCIUM SALT
AH23848 hemicalcium salt
(4Z)-7-[(rel-1S,2S,5R)-5-((1,1′-Biphenyl-4-yl)methoxy)-2-(4-morpholinyl)-3-oxocyclopentyl]- 4-heptenoic acid hemicalcium salt
COFQPJQSNPAAKY-LCCMWPRESA-M
81496-19-7
C29H34NO512Ca

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