ovatodiolide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ovatodiolide (OV) is a bioactive phytochemical purified from Anisomeles indica (L.) Kuntze (Labiatae) is a medicinal herb that has been widely used to treat a variety of inflammation-associated diseases. Ovatodiolide has been reported to exhibit many biological functions, including anti-cancer, anti-bacterial, and anti-HIV activities. Most importantly, the studies have demonstrated that ovatodiolide inhibited H. pylori-induced inflammation in gastric epithelial cells[1-2].
Toxicity evaluation
In the bacterial reverse mutation assay and the mammalian chromosome aberration assay, ovatodiolide was non-mutagenic with or without the addition of the S9 fraction. In the micronucleus assay, ovatodiolide did not cause an increase in micronucleated reticulocytes. The acute oral toxicity of ovatodiolide in rats exceeded 1000 mg/kg bw. In addition, ovatodiolide at 10, 25, and 50 mg/kg bw did not produce significant effects in rats
[3].
ovatodiolide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
