3-Bromo-2-naphthol
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- CAS-Nr.
- 30478-88-7
- Englisch Name:
- 3-Bromo-2-naphthol
- Synonyma:
- 3-broMonaphthalen-2-ol;3-Bromo-2-naphthol;3-Bromo-2-naphthol >3-bromo-2-naphthalenol;3-Bromo-2-naphthol 99%;2-NAPHTHALENOL, 3-BROMO-;2-NAPHTHALENOL, 3-BROMO- ISO 9001：2015 REACH
- CBNumber:
- CB21474099
- Summenformel:
- C10H7BrO
- Molgewicht:
- 223.07
- MOL-Datei:
- 30478-88-7.mol
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3-Bromo-2-naphthol Eigenschaften
- Schmelzpunkt:
- 82 °C
- Siedepunkt:
- 313.7±15.0 °C(Predicted)
- Dichte
- 1.614±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Aggregatzustand
- powder to crystal
- pka
- 8.03±0.40(Predicted)
- Farbe
- White to Light yellow
- InChI
- 1S/C10H7BrO/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-6,12H
- InChIKey
- PQVIOPAWVAOHOA-UHFFFAOYSA-N
- SMILES
- Oc1cc2ccccc2cc1Br
- CAS Datenbank
- 30478-88-7
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
37/38-41 |
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| S-S?tze: |
26-39 |
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| WGK Germany |
3 |
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| HS Code |
2908.19.6000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H318 |
Verursacht schwere Augensch?den. |
Schwere Augensch?digung |
Kategorie 1 |
Achtung |
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P280, P305+P351+P338, P310 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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3-Bromo-2-naphthol Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
3-Bromo-2-naphthol is synthesised using 2-bromo-3-methoxynaphthalene as a raw material by chemical reaction. The specific synthesis steps are as follows:
General procedure: To a Schlenk flask were added 2-bromo-3-methoxynaphthalene(1.0 equiv), aryl boronic acid (2.2 equiv), K
2CO
3 (3.0 equiv), Pd(PPh3)4 (2.5 mol%), and degassed EtOH/toluene/water (1/1/1) under Ar atmosphere. The mixture was heated at 90 °C until thecompletion of the reaction. Then the mixture was cooled to room temperature, and DCM was added. The mixture was washed with NaOH solution (20% wt), and the aqueous phase was extracted with DCM (2 × 20 mL). The combined organic phase was washed with brine (20 mL) and dried overanhydrous MgSO
4. After removing the solvent, the residue was dissolved in anhydrous DCM. Thesolution was cooled to -78 °C, and BBr3 (1 M in DCM, 5.0 equiv) was added slowly by syringe. Thenthe mixture was warmed up to room temperature and stirred until the complete consumption of thestarting material. The mixture was poured into the ice water (50 mL) and extracted with DCM (3 × 50mL). The combined organic phase was washed with brine (100 mL) and dried over anhydrous Na
2SO4. After removing the solvent, the residue was purified by silica gel chromatography to give 3-Bromo-2-naphthol.
3-Bromo-2-naphthol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Bromo-2-naphthol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 106)Lieferanten
30478-88-7()Verwandte Suche:
- 2-NAPHTHALENOL, 3-BROMO-
- 3-Bromo-2-naphthol 99%
- 3-bromo-2-naphthalenol
- 3-Bromo-2-naphthol >
- 2-NAPHTHALENOL, 3-BROMO- ISO 9001：2015 REACH
- 3-Bromo-2-naphthol
- 3-broMonaphthalen-2-ol
- 30478-88-7
- Building Blocks
- C9 to C20+
- Chemical Synthesis
- Organic Building Blocks
- Oxygen Compounds
- Organic Building Blocks
- Oxygen Compounds
- Phenols
