Stiripentol
|
|
|
- CAS-Nr.
- 49763-96-4
- Bezeichnung:
- Stiripentol
- Englisch Name:
- STIRIPENTOL
- Synonyma:
- Diacomit;bcx2600;RCX-2600;Slipperto;STIRIPENTOL;Stiripentol >BCX2600|||Diacomit;Stiripentol, ≥ 98.0%;Stiripentol(BCX 2600);STIRIPENTOL USP/EP/BP
- CBNumber:
- CB2150457
- Summenformel:
- C14H18O3
- Molgewicht:
- 234.29
- MOL-Datei:
- 49763-96-4.mol
|
Stiripentol Eigenschaften
- Schmelzpunkt:
- 73-74°C
- Siedepunkt:
- 365.4±11.0 °C(Predicted)
- Dichte
- 1.139±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: ≥20mg/mL
- pka
- 14.45±0.20(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
- InChI
- InChI=1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3
- InChIKey
- IBLNKMRFIPWSOY-FNORWQNLSA-N
- SMILES
- C(C1=CC=C2OCOC2=C1)=CC(O)C(C)(C)C
- CAS Datenbank
- 49763-96-4
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
|
|
| R-S?tze: |
22 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
SB3393000 |
|
|
| HS Code |
2932.99.7000 |
|
|
| Speicherklasse |
11 - Combustible Solids |
|
|
| Hazard Classifications |
Acute Tox. 4 Oral |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
|
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
Stiripentol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABA
A receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing α
3 subunits and to a lower extent in those containing β
1 or ε subunits. It also inhibits GABA reuptake
in vitro and increases the release of GABA in neonatal rat hippocampal slices. Stiripentol (500 μM) inhibits lactate dehydrogenase (LDH), blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human LDH1 and LDH5. Formulations containing stiripentol have been used in the adjunctive treatment of seizures associated with Dravet syndrome.
Chemische Eigenschaften
White Solid
Verwenden
Stiripentol is an epilepsy drug, it has been used as co-therapy for treatment of epilepsy.
Stiripentol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Stiripentol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 215)Lieferanten
49763-96-4(Stiripentol)Verwandte Suche:
- (RS)-(E)-4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol
- 1-(1,3-BENZODIOXOL-5YL)-4,4-DIMETHYL-1-PENTEN-3-OL
- STIRIPENTOL
- 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-o
- 4,4-dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-o
- 4,4-dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-ol
- bcx2600
- 1-(Benzo[d][1,3]dioxol-5-yl)-4,4-dimethylpent-1-en-3-ol
- RCX-2600
- 1-PENTEN-3-OL, 1-(1,3-BENZODIOXOL-5-YL)-4,4-DIMETHYL-
- Stiripentol(BCX 2600)
- Stiripentol >
- STIRIPENTOL USP/EP/BP
- 1-(1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol
- StiripentolQ: What is
Stiripentol Q: What is the CAS Number of
Stiripentol Q: What is the storage condition of
Stiripentol Q: What are the applications of
Stiripentol
- Z-alpha-Methylcinnamaldehyde
- Diacomit
- 1H-Benzimidazole-1-acetonitrile,2,3-dihydro-6-oxo-
- Stiripentol, ≥ 98.0%
- BCX2600|||Diacomit
- Stiripentol Impurity A
- Slipperto
- Stiripentol, 10 mM in DMSO
- 1-(1,3-benzenebenzodioxypentylcyclo-5-yl)-4,4-dimethyl-1-pentylene-3-ol
- Stiripentol reference standard
- Stiripentol (Standard)
- 49763-96-4
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- APIs
