Calhex 231 Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White Solid

Verwenden

Calhex 231 hydrochloride has been used:

• as a calcium-sensing receptor (CaSR) antagonist: to test its impact on hearing in rats
• to test its effect on blood pressure levels spontaneous hypertensive rats (SHRs)
• to test its effect on acoustic response bias in zebrafish
• in Caco-2 cells to test its effect on, overexpression of fibroblast growth factor-23 (FGF-23 )

Biochem/physiol Actions

Calhex 231 is a negative allosteric modulator of the calcium sensing receptor CaSR. Calhex 231 blocks calcium-induced accumulation of inositol phosphate with an IC50 of 0.36 μM.

Calhex 231 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Calhex 231 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57422	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
TCI (Shanghai) Chemical Trading Co., Ltd.	021-61109150	sales@tcisct.com	China	29717	58

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• 4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide
• Calhex 231
• 4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride
• Calhex-231 (Calhex231)
• Benzamide, 4-chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-
• Calhex 231 hydrochloride
• 652973-93-8
• C25H27ClN2O
• Chiral Reagents
• Intermediates & Fine Chemicals
• Pharmaceuticals