Anti-GOK, Anti-Stromal interaction molecule I Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-STIM1 (N-terminal) antibody produced in rabbit has been used in:

• western blotting
• immunoprecipitation
• immunofluorescence

Allgemeine Beschreibung

STIM1 (stromal interaction molecule 1) is a conserved single-pass transmembrane protein, which is expressed ubiquitously in a wide variety of human primary and transformed cell types. STIM1 is modified by phosphorylation and N-linked glycosylation. STIM1 localized predominantly in the membrane of the endoplasmic reticulum (ER). It contains an N-terminal EF hand motif located in the ER lumen and appears to function as a sensor of ER Ca²⁺ levels.

Biochem/physiol Actions

STIM1 (stromal interaction molecule 1) is required for the activation of store-operated Ca2+ influx. Overexpression of STIM1 and Orai1 markedly increases the calcium release-activated calcium (CRAC) current (I-CRAC).

Anti-GOK, Anti-Stromal interaction molecule I Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Anti-GOK, Anti-Stromal interaction molecule I Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

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• Anti-STIM1 (N-terminal) antibody produced in rabbit
• Anti-GOK, Anti-Stromal interaction molecule I