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CALPAIN INHIBITOR XII

CALPAIN INHIBITOR XII Struktur
181769-57-3
CAS-Nr.
181769-57-3
Englisch Name:
CALPAIN INHIBITOR XII
Synonyma:
CALPAIN INHIBITOR XII;Z-L-NVA-CONH-CH2-2-PY;PLVWMBFPIAQRHK-UHFFFAOYSA-N;(Rac)-Calpain Inhibitor XII;benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate;Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
CBNumber:
CB2243292
Summenformel:
C26H34N4O5
Molgewicht:
482.57
MOL-Datei:
Mol file

CALPAIN INHIBITOR XII Eigenschaften

Dichte
1.167±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≤16mg/ml in ethanol;16mg/ml in DMSO;20mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
pka
10.58±0.46(Predicted)
Farbe
White to yellow

Sicherheit

CALPAIN INHIBITOR XII Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki = 19 nM), with lower affinities for calpain II (m-calpain, Ki = 120 nM) and cathepsin B (Ki = 750 nM). Calpain inhibitors, including this compound, have been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

Verwenden

A cell-permeable dipeptidyl -ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1

CALPAIN INHIBITOR XII Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CALPAIN INHIBITOR XII Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 50)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
16314854226; +8616314854226
inquiry@bocsci.com United States 19852 58
Nantong HI-FUTURE Biology Co., Ltd.
+86-18051384581
sales@chemhifuture.com China 3123 58
Wuhan Topule Biopharmaceutical Co., Ltd
+86-18327326525
masar@topule.com China 8433 58
Aladdin Scientific

tp@aladdinsci.com United States 52906 58
NANJING YINGWEN BIOTECHNOLOGY CO LTD
+86-13382787392
sales@aeechem.com China 10002 58
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
BOC Sciences 16314854226
info@bocsci.com United States 9909 65
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518
shyysw007@163.com China 89667 60
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799
Eric@peptidego.com China 7858 58
Angel Pharmatech, Ltd. 17317130613
3358272972@qq.com China 3305 58

  • Z-L-NVA-CONH-CH2-2-PY
  • CALPAIN INHIBITOR XII
  • (Rac)-Calpain Inhibitor XII
  • Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
  • PLVWMBFPIAQRHK-UHFFFAOYSA-N
  • benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
  • 181769-57-3
  • C26H34N4O5
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