5-benzoylaminoindole
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- CAS-Nr.
- 6019-39-2
- Englisch Name:
- 5-benzoylaminoindole
- Synonyma:
- OAC2;CS-2128;OAC2?, >98%;OAC-2;OAC 2;OAC2 ，S5915;OAC2, 10 mM in DMSO;5-benzoylaminoindole;N-(1H-Indol-5-yl)benzaMide;Benzamide, N-1H-indol-5-yl-
- CBNumber:
- CB22523495
- Summenformel:
- C15H12N2O
- Molgewicht:
- 236.27
- MOL-Datei:
- 6019-39-2.mol
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5-benzoylaminoindole Eigenschaften
- Schmelzpunkt:
- 165 - 167°C
- Siedepunkt:
- 364.3±15.0 °C(Predicted)
- Dichte
- 1.307±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.99±0.43(Predicted)
- Farbe
- Pale Yellow
- InChI
- 1S/C15H12N2O/c18-15(11-4-2-1-3-5-11)17-13-6-7-14-12(10-13)8-9-16-14/h1-10,16H,(H,17,18)
- InChIKey
- JCAFGYWSIWYMOX-UHFFFAOYSA-N
- SMILES
- O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC=CC=C3
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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5-benzoylaminoindole Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-
Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells. OAC2 is an Oct4-
activating compound which activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-
Myc, OAC2 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts. The iPSCs developed using OAC2 retain the capacity for pluripotent differentiation, whether evaluated
in vitro or
in vivo.
Verwenden
N-(1H-Indol-5-yl)benzamide is a octamer-binding transcription factor 4 activating compound that activated Oct4 and Nanog promoters, which are essential regulators of embryonic stem cell (ESC) pluripotency and key to the reprogramming process.
5-benzoylaminoindole Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-benzoylaminoindole Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 109)Lieferanten
- 5-benzoylaminoindole
- N-(1H-Indol-5-yl)benzaMide
- CS-2128
- OAC-2;OAC 2
- OAC2?, >98%
- Benzamide, N-1H-indol-5-yl-
- OAC2, 10 mM in DMSO
- OAC2 ，S5915
- OAC2
- 6019-39-2
- Inhibitors
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
