2'-deoxy-2'-fluoro-2'-C-methylcytidine

817204-33-4

CAS-Nr.: 817204-33-4

Englisch Name:: 2'-deoxy-2'-fluoro-2'-C-methylcytidine

Synonyma:: ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130(R 1656);PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130, 10 mM in DMSO;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine

CBNumber:: CB22525888

Summenformel:: C10H14FN3O4

Molgewicht:: 259.23

MOL-Datei:: 817204-33-4.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 159

2'-deoxy-2'-fluoro-2'-C-methylcytidine Eigenschaften

Schmelzpunkt:: 216-218℃

Siedepunkt:: 482.4±55.0 °C(Predicted)

Dichte: 1.67

storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere

L?slichkeit: Methanol (Slightly), Water (Slightly)

pka: 12.86±0.70(Predicted)

Aggregatzustand: Solid

Farbe: White to Light Brown

Stabilit?t:: Hygroscopic

InChI: InChI=1S/C10H14FN3O4/c1-10(11)7(16)5(4-15)18-8(10)14-3-2-6(12)13-9(14)17/h2-3,5,7-8,15-16H,4H2,1H3,(H2,12,13,17)/t5-,7-,8-,10-/m1/s1

InChIKey: NYPIRLYMDJMKGW-VPCXQMTMSA-N

SMILES: OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@@](F)(C)[C@@H]1O

Sicherheit

Risiko- und Sicherheitserkl?rung
Gefahreninformationscode (GHS)

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	P-Code
H302	Gesundheitssch?dlich bei Verschlucken.	Akute Toxizit?t oral	Kategorie 4	Warnung	P264, P270, P301+P312, P330, P501
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	P264, P280, P305+P351+P338,P337+P313P
H335	Kann die Atemwege reizen.	Spezifische Zielorgan-Toxizit?t (einmalige Exposition)	Kategorie 3 (Atemwegsreizung)	Warnung

Sicherheit

P261	Einatmen von Staub vermeiden.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; K_i = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC₅₀s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC₅₀ values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC₉₀s = 46.3, >100, >100, and >10 μM, respectively).

Verwenden

PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.

2'-deoxy-2'-fluoro-2'-C-methylcytidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2'-deoxy-2'-fluoro-2'-C-methylcytidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 159)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Hefei Lbao Physical & Chemical Science Co.,Ltd	+15184799099	lbaochemicals@gmail.com	China	670	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21586	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58

817204-33-4()Verwandte Suche:

3-Aminobenzotrifluorid

(2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine
PSI-6130;R 1656;PSI 6130
4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr
2'-deoxy-2'-fluoro-2'-C-methylcytidine
R 1656
ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate
4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi
4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one
R 1656; R-1656; R1656; PSI6130; PSI 6130
2'-deoxy-2'-fluoro-2'-C-methylcytidin
2'-Deoxy-2'-F-2'-C-methylcytidine
CS-1995
PSI-6130;PSI 6130
Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-
2'-deoxy-2'-fluoro-2'-C-methylcytidine,817204-33-4
ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate
PSI 6130
2'-deoxy-2'-Fluoro-2'-methylcytidine
4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one (sofosbuvir Impurity)
Sofosbuvir Impurity 121
2'-C-methyl-2'-Fluoro-2'-deoxyCytidine
PSI-6130(R 1656)
(2'R)-2'-deoxy-2'-fluoro-2'-methylcytidine
PSI-6130, 10 mM in DMSO
2'-deoxy-2'-fluoro-2'-C-methylcytidine,PSI-6130
817204-33-4
apis

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