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Methyl trans-3-(boc-amino)cyclobutanecarboxylate

Methyl trans-3-(boc-amino)cyclobutanecarboxylate Struktur
1101173-77-6
CAS-Nr.
1101173-77-6
Englisch Name:
Methyl trans-3-(boc-amino)cyclobutanecarboxylate
Synonyma:
Methyl trans-3-(Boc-aMino...;Methyl trans-3-(Boc-aMino)cyclobutanecarboxylate;Methyl trans-3-(Boc-amino)cyclobutanecarboxylate - SB7936;methyl trans-3-(tert-butoxycarbonylamino)cyclobutanecarboxylate;trans-Methyl 3-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate;methyl (1r,3r)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate;methyl 3-[(2-methylpropan-2-yl)oxycarbonylamino]cyclobutane-1-carboxylate;rac-methyl (1r,3r)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate;Cyclobutanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, trans-
CBNumber:
CB22552891
Summenformel:
C11H19NO4
Molgewicht:
229.27
MOL-Datei:
1101173-77-6.mol

Methyl trans-3-(boc-amino)cyclobutanecarboxylate Eigenschaften

Siedepunkt:
314.1±31.0 °C(Predicted)
Dichte
1.10±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.05±0.40(Predicted)
Aggregatzustand
solid
Farbe
White
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
HS Code  2922498590
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Methyl trans-3-(boc-amino)cyclobutanecarboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Synthese

Methyl /rara-3-amino-cyclobutanecarboxylate hydrochloride (39.94 g, 241 mmol) was suspended in dichloromethane (400 ml). The solution was cooled to 0°C before Et3N (4 equiv., 134 ml, 965 mmol) and Boc anhydride (1.2 equiv., 63.2 g, 289 mmol) were added. The cooling bath was removed and the mixture was stirred while slowly allowing to warm up to room temperature. After 20 hours of stirring, the salts were filtered off and the filtrate was rinsed three times with water. The organic layer was dried over sodium sulfate, filtered and concentrated in vacuo. The residue was triturated in heptane, the solid was filtered off and dried in air flow to give Methyl trans-3-(boc-amino)cyclobutanecarboxylate as a white solid.
Cyclobutanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, trans-

Methyl trans-3-(boc-amino)cyclobutanecarboxylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Methyl trans-3-(boc-amino)cyclobutanecarboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Methyl trans-3-(Boc-aMino)cyclobutanecarboxylate
  • trans-Methyl 3-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate
  • Methyl trans-3-(Boc-amino)cyclobutanecarboxylate - SB7936
  • methyl 3-[(2-methylpropan-2-yl)oxycarbonylamino]cyclobutane-1-carboxylate
  • Cyclobutanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, trans-
  • methyl trans-3-(tert-butoxycarbonylamino)cyclobutanecarboxylate
  • Methyl trans-3-(Boc-aMino...
  • methyl (1r,3r)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate
  • rac-methyl (1r,3r)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate
  • 1101173-77-6
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