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5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Struktur
145915-60-2
CAS-Nr.
145915-60-2
Englisch Name:
5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
Synonyma:
DAPH-7;DAPH 2;CGP 53353;CGP-53353 solid;CGP 53353, 10 mM in DMSO;PKCβII/EGFR Inhibitor;5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione;PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem;5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE;5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
CBNumber:
CB2299648
Summenformel:
C20H13F2N3O2
Molgewicht:
365.33
MOL-Datei:
145915-60-2.mol

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Eigenschaften

storage temp. 
2-8°C
L?slichkeit
DMSO: >10mg/mL
Aggregatzustand
solid
Farbe
orange
InChI
1S/C20H13F2N3O2/c21-11-1-5-13(6-2-11)23-17-9-15-16(20(27)25-19(15)26)10-18(17)24-14-7-3-12(22)4-8-14/h1-10,23-24H,(H,25,26,27)
InChIKey
RONQPWQYDRPRGG-UHFFFAOYSA-N

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CGP 53353 inhibited tyrosine kinase activity of the EGF-R in five different human transitional cell carcinoma lines.

Biologische Aktivit?t

Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro .

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 43)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Aladdin Scientific

tp@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037
3bsc@sina.com China 15838 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9804 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
3008007409@qq.com China 89686 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686
sales@rechemscience.com China 2985 58
Changzhou Chenhong Biotechnology Co., Ltd. +86-0519-85788828 +86-13775037613
sales@chemrenpharm.com China 4058 58

  • CGP 53353
  • 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE
  • 5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE
  • 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2
  • DAPH 2
  • DAPH-7
  • PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem
  • 1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]-
  • CGP-53353 solid
  • 5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione
  • CGP 53353, 10 mM in DMSO
  • PKCβII/EGFR Inhibitor
  • 145915-60-2
  • C20H13F2N3O2
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Protein Kinase C (PKC)
  • Kinase/Phosphatase Biology
  • Serine/Threonine Kinase Inhibitors
  • Protein Kinase
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