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Vinflunine

Vinflunine Struktur
162652-95-1
CAS-Nr.
162652-95-1
Englisch Name:
Vinflunine
Synonyma:
Vinflunine Tartrate;VINFLUNINE;vinflunine(97%);Vinflunine (F12158);Vinflunine USP/EP/BP;Vinflunine 162652-95-1;20',20'-Difluoro-3',4'-dihydrovinorelbine;4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine;4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine;Aspidospermidine-3-carboxylicacid,4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-1
CBNumber:
CB2358406
Summenformel:
C45H54F2N4O8
Molgewicht:
816.94
MOL-Datei:
162652-95-1.mol

Vinflunine Eigenschaften

Dichte
1.39±0.1 g/cm3(Predicted)
pka
11.36±0.60(Predicted)
CAS Datenbank
162652-95-1(CAS DataBase Reference)

Sicherheit

Vinflunine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Vinflunine (also referred to as PM391) is a semisynthetic analog of the natural vinca alkaloids vinblastine and vincristine that was approved by the European Medicines Agency (EMEA) in 2009 for the treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regimen. Vinflunine is synthesized from anhydrovinblastine in a superacid media (HF-SbF5) and in the presence of a chlorinated solvent like CHCl3 or CCl4.

Definition

ChEBI: An organic heteropentacyclic compound and an organic heterotetracyclic compound that is vinorelbine in which the tetrahydropyridine moiety of the heterotetracyclic part of the molecule has been redced to the corresponding piperidine, and in which the ethy group attached to this ring has been replaced by a 1,1-difluoroethyl group.

Vinflunine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Vinflunine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 99)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29815 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202
sale02@cqherb.com CHINA 376 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17346 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 20584 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15073 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471;
sales@sarms4muscle.com China 10473 58
changzhou huayang technology co., ltd
+8615250961469
2571773637@qq.com China 9653 58

162652-95-1()Verwandte Suche:


  • VINFLUNINE
  • 20',20'-Difluoro-3',4'-dihydrovinorelbine
  • 4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine
  • 4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine
  • Vinflunine 162652-95-1
  • Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
  • Vinflunine USP/EP/BP
  • Vinflunine (F12158)
  • Aspidospermidine-3-carboxylicacid,4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-1
  • vinflunine(97%)
  • Vinflunine Tartrate
  • 162652-95-1
  • C45H54F2N4O8
  • Miscellaneous Natural Products
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